From: Insulin versus oral agents in the management of Cystic Fibrosis Related Diabetes: a case based study
Variable Mean ± SD (Range) | Insulin (n = 8) | Sulfonylurea (n = 5) | Metformin (n = 6) | Thiazoli-dinediones (n = 6) | P Value |
---|---|---|---|---|---|
Age (Yrs) | 26.0 ± 10.3 (13 – 44) | 24.4 ± 6.9 (17 – 33) | 22.8 ± 6.7 (15 – 35) | 34.0 ± 9.9 (20 – 49) | 0.166 |
ALT (U/L) | 65.1 ± 24.1 (25 – 99) | 42.0 ± 26.5 (14 – 73) | 68.3 ± 28.1 (28 – 107 | 67.4 ± 8.4 (55 – 76) (n = 5) | 0.250 |
FEV1 (%) | 56.8 ± 28.0 (18 – 99) | 53.0 ± 23.3 (30 – 83) | 79.2 ± 34.5 (17 – 117) | 52.0 ± 25.2 (3 – 92) | 0.329 |
Weight (kg) | 60.2 ± 12.9 (41.9 – 81.5) | 66.0 ± 24.8 (33.6 – 97.5) | 61.8 ± 12.2 (41.8 – 71.1) | 65.7 ± 20.4 (44.4 – 96.5) | 0.911 |
HbA1c | 9.5 ± 2.6 (5.5 – 14.3) | 7.2 ± 0.8 (6.3 – 8.1) | 8.8 ± 2.8 (5.4 – 13.3) | 8.0 ± 3.1 (5.1 – 13.3) | 0.408 |
Treatment Duration (Yrs) | 4.8 ± 2.9 (2 – 10) | 1.8 ± 1.3 (1 – 4) | 2.7 ± 1.4 (1 – 5) | 1.8 ± 0.4 (1 – 2) | 0.093 |