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Table 2 Baseline clinical data

From: Insulin versus oral agents in the management of Cystic Fibrosis Related Diabetes: a case based study

Variable Mean ± SD (Range)

Insulin (n = 8)

Sulfonylurea (n = 5)

Metformin (n = 6)

Thiazoli-dinediones (n = 6)

P Value

Age (Yrs)

26.0 ± 10.3 (13 – 44)

24.4 ± 6.9 (17 – 33)

22.8 ± 6.7 (15 – 35)

34.0 ± 9.9 (20 – 49)

0.166

ALT (U/L)

65.1 ± 24.1 (25 – 99)

42.0 ± 26.5 (14 – 73)

68.3 ± 28.1 (28 – 107

67.4 ± 8.4 (55 – 76) (n = 5)

0.250

FEV1 (%)

56.8 ± 28.0 (18 – 99)

53.0 ± 23.3 (30 – 83)

79.2 ± 34.5 (17 – 117)

52.0 ± 25.2 (3 – 92)

0.329

Weight (kg)

60.2 ± 12.9 (41.9 – 81.5)

66.0 ± 24.8 (33.6 – 97.5)

61.8 ± 12.2 (41.8 – 71.1)

65.7 ± 20.4 (44.4 – 96.5)

0.911

HbA1c

9.5 ± 2.6 (5.5 – 14.3)

7.2 ± 0.8 (6.3 – 8.1)

8.8 ± 2.8 (5.4 – 13.3)

8.0 ± 3.1 (5.1 – 13.3)

0.408

Treatment Duration (Yrs)

4.8 ± 2.9 (2 – 10)

1.8 ± 1.3 (1 – 4)

2.7 ± 1.4 (1 – 5)

1.8 ± 0.4 (1 – 2)

0.093

  1. SD, standard deviation; Yrs, years; ALT, alanine aminotransferase; FEV1, forced expiratory volume at 1 second; HbA1c, percent glycosylated hemoglobin. P values for Age, ALT, FEV1, Weight, and HbA1c are from one-way analysis of variance (ANOVA); the P value for Treatment Duration is from Welch ANOVA for unequal group variances.