Table 5 The prevalence of hypothyroidism in the IFN-naïve and IFN-treated HCV patients compared with the general populations. The prevalence of elevated TSH levels in the various population groups include: Australia ~2.0% [17], the United States of America ~7.3% [18], Spain ~2.0% [18], Japan ~1.3% [18], Great Britain ~7.3% [18] and Italy ~1.7% [19]
Studies N = number of subjects | Prevalence of hypothyroidism (before IFN) | Prevalence of hypothyroidism (after IFN) |
|---|---|---|
Marcellin et al. [5] N = 74 | 0 | 7.2 |
Preziati et al. [15] N = 78 | 0 | 22.8 |
Imigawa et al. [14] N = 58 | 0 | 3.4 |
Marazuela et al. [7] N = 207 | 4.7 | 2.8 |
This work N = 272 | 1.1% | 7.5% |
Baudin et al. [16] N = 68 | 0 | 7.3 |
Antonelli et al. [13] N = 630 | 13% | N/A |