Table 4 Data for hypothyroid patients receiving combination therapy for Hepatitis C infection
Number of subjects | 15 (9 treated for 48 weeks and 6 for 24 weeks) |
|---|---|
Gender | 3 M : 12 F |
Mean age | 44 ± 2 |
Positive family history of thyroid disease (in first degree relatives) | 8/18 (44%) |
Duration of IFN-α before thyroid disease developed (months) | 4.8 ± 1.2 |
Mean TSH levels (mU/L) | 29.7 ± 8.8 |
Mean fT4 levels (pmol/L) | 3.5 ± 0.9 |
The presence of TPO-autoantibodies | 6/15 (40%) |
Thyroxine requirement at the 12-month follow-up | 13/15 (87%) |
PCR negativity at the end of treatment | 15/15 (100%) |