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Table 3 Results of the linear regression analyses for the relationship between birth weight and adult risk factors for CVD and DM-2

From: An IGF-I promoter polymorphism modifies the relationships between birth weight and risk factors for cardiovascular disease and diabetes at age 36

 

Crude†

Adjusted ‡

Outcome

β

95%CI

β

95%CI

Body mass index (kg/m2)

0.445

[-0.264; 1.154]

  

Fat-mass (kg)

0.962

[-0.361; 2.285]

-0.663

[-1.605; 0.208]

Fat-free mass (kg)

2.553***

[1.224; 3.882]

0.714

[-0.085; 1.513]

Waist circumference (cm)

1.760

[-0.372; 3.892]

-1.013

[-2.253; 0.227]

Waist-to-hip ratio

0.012

[-0.005; 0.028]

0.006

[-0.011; 0.022]

Systolic blood pressure (mmHg)

-1.387

[-4.082; 1.309]

-3.050*

[-5.626; -0.475]

Diastolic blood pressure (mmHg)

-0.692

[-2.445; 1.071]

-1.608

[-3.329; 0.113]

Resting heart rate (b/min)

1.941

[-0.932; 4.815]

1.861

[-1.081; 4.803]

Low density lipoprotein (mmol/l)

-0.079

[-0.277; 0.118]

-0.154

[-0.351; 0.044]

Carotid intima-media thickness (mm) ∥

0.011

[-0.012; 0.034]

0.011

[-0.012; 0.035]

Glycated hemoglobin (%)

-0.013

[-0.109; 0.082]

-0.025

[-0.123; 0.072]

  1. Data is presented as regression coefficients and corresponding 95% confidence intervals (CI)
  2. CVD – cardiovascular disease; DM-2 – type 2 diabetes mellitus
  3. † Crude, only adjusted for gender; ‡, Adjusted, further adjusted for adult body weight
  4. * p < 0.05 *** p < 0.001
  5. ∥ also adjusted for systolic and diastolic blood pressure