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Table 3 Results of the linear regression analyses for the relationship between birth weight and adult risk factors for CVD and DM-2

From: An IGF-I promoter polymorphism modifies the relationships between birth weight and risk factors for cardiovascular disease and diabetes at age 36

  Crude† Adjusted ‡
Outcome β 95%CI β 95%CI
Body mass index (kg/m2) 0.445 [-0.264; 1.154]   
Fat-mass (kg) 0.962 [-0.361; 2.285] -0.663 [-1.605; 0.208]
Fat-free mass (kg) 2.553*** [1.224; 3.882] 0.714 [-0.085; 1.513]
Waist circumference (cm) 1.760 [-0.372; 3.892] -1.013 [-2.253; 0.227]
Waist-to-hip ratio 0.012 [-0.005; 0.028] 0.006 [-0.011; 0.022]
Systolic blood pressure (mmHg) -1.387 [-4.082; 1.309] -3.050* [-5.626; -0.475]
Diastolic blood pressure (mmHg) -0.692 [-2.445; 1.071] -1.608 [-3.329; 0.113]
Resting heart rate (b/min) 1.941 [-0.932; 4.815] 1.861 [-1.081; 4.803]
Low density lipoprotein (mmol/l) -0.079 [-0.277; 0.118] -0.154 [-0.351; 0.044]
Carotid intima-media thickness (mm) 0.011 [-0.012; 0.034] 0.011 [-0.012; 0.035]
Glycated hemoglobin (%) -0.013 [-0.109; 0.082] -0.025 [-0.123; 0.072]
  1. Data is presented as regression coefficients and corresponding 95% confidence intervals (CI)
  2. CVD – cardiovascular disease; DM-2 – type 2 diabetes mellitus
  3. † Crude, only adjusted for gender; ‡, Adjusted, further adjusted for adult body weight
  4. * p < 0.05 *** p < 0.001
  5. also adjusted for systolic and diastolic blood pressure