Table 2 Percent blood glucose reduction (Mean ± SEM) with L-ascorbic acid/ tolbutamide / L-ascorbic acid + tolbutamide in diabetic rats (n = 5)
Time in hours | L-ascorbic acid 40 mg/kg bd.wt. | Tolbutamide 20 mg/kg bd.wt. | L-ascorbic acid 40 mg/kg bd.wt. + Tolbutamide 20 mg/kg bd.wt. |
|---|---|---|---|
0 | - | - | - |
0.5 | 18.23 ± 1.88 | 3.03 ± 0.8 | 23.55 ± 2.37*** |
1 | 35.45 ± 3.26 | 7.83 ± 1.84 | 35.59 ± 4.48*** |
1.5 | 42.53 ± 1.78 | 18.58 ± 2.49 | 57.49 ± 1.63** |
2 | 34.04 ± 2.22 | 37.97 ± 6.40 | 59.74 ± 1.22* |
4 | 20.02 ± 3.32 | 45.09 ± 4.95 | 62.55 ± 0.64** |
6 | - | 21.6 ± 1.94 | 39.43 ± 2.15*** |