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Table 3 Clinical and epidemiological characteristics of patients with and without DM separated to cirrhosis and chronic hepatitis groups

From: Prevalence and determinants of diabetes mellitus among Iranian patients with chronic liver disease

  Patients with cirrhosis Patients with chronic hepatitis
  Diabetic Non-diabetic P-value Diabetic Non-diabetic P-value
Number 22 19   14 88  
Sex    NS    NS
   Female 4 (18.2%) 3 (15.8%)   2 (14.3%) 12 (13.6%)  
   Male 18 (81.8%) 16 (84.2%)   12 (85.7%) 76 (86.4%)  
Age 56.9 ± 10.6 46.6 ± 10.0 0.003 49.7 ± 7.8 39.9 ± 10.7 0.001
CLD etiology    NS    NS
   HBV 11 (50.0%) 13 (68.4%)   10 (71.4%) 37 (42.0%)  
   HCV 8 (36.4%) 4 (21.1%)   4 (28.6%) 51 (58.0%)  
   Criptogenic 3 (13.6%) 2 (10.5%)   - -  
Family history of DM    NS    0.01
   Yes 9 (40.9%) 3 (15.8%)   8 (57.1%) 21 (23.9%)  
   No 13 (59.1%) 16 (84.2%)   6 (42.9%) 67 (76.1%)  
History of hypertension    NS    NS
   Yes 6 (27.3%) 1 (5.3%)   3 (21.4%) 8 (9.1%)  
   No 16 (72.7%) 18 (94.7%)   11 (78.6%) 80 (90.9%)  
BMI 26.4 ± 3.4 26.4 ± 4.0 NS 27.7 ± 4.8 24.5 ± 3.1 0.02
Interferon therapy    NS    NS
   Yes 2 (9.1%) 3 (15.8%)   4 (28.6%) 46 (52.3%)  
   No 20 (90.9%) 16 (84.2%)   10 (71.4%) 42 (47.7%)  
Smoking    NS    NS
   Yes 5 (22.7%) 5 (26.3%)   7 (50.0%) 25 (28.4%)  
   No 17 (77.3%) 14 (73.7%)   7 (50.0%) 63 (71.6%)  
TG 145.5 ± 58.6 109.3 ± 75.2 NS 174.9 ± 82.5 140.6 ± 53.8 NS
Chol 141.6 ± 50.5 151.8± 32.5 NS 199.8 ± 42.8 163.9 ± 36.1 NS
Child-Pugh's score    0.04    
   Score A 13 (65.0%) 18 (94.7%)   - - -
   Score B 7 (35.0%) 1 (5.3%)     
Histological staging*       0.003
   0–1 - - - 1 (8.3%) 33 (41.8%)  
   2–3     3 (25.0%) 30 (38.0%)  
   4–6     8 (66.7%) 16 (20.3%)  
Histological grading*       NS
   0–4 - - - 2 (16.7%) 36 (45.6%)  
   5–8     8 (66.7%) 34 (43.0%)  
   ≥ 9     2 (16.7%) 9 (11.4%)  
  1. * According to Knodell score