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Table 2 Demographic characteristics of subjects in included studies

From: A systematic review of the literature examining the diagnostic efficacy of measurement of fractionated plasma free metanephrines in the biochemical diagnosis of pheochromocytoma

Demographic characteristic Mayo Clinic* NIH Vienna
Years of recruitment of patients 1999–2001 1994–2001 Unclear
Proportion of female gender of all patients 287/507 (57%) 475/858 (55%) 24/31 (77%)
Proportion of sporadic pheochromocytoma patients (%) 39/56 (70%) 138/214 (64%) 14/17 (82%)
Proportion of non-pheochromocytoma patients with no genetic predisposition to disease† 399/445 (90%) 305/644 (47%) Unclear
Mean age, years (range) of all pheochromocytoma patients 49 (16–83) 33,47‡ (8–78) 46
Mean age, years (range) of all non-pheochromocytoma patients 52 (7–86) 38,47‡ (8–77) 44
  1. *Published Mayo Clinic data was supplemented with new data. † Subjects with sporadic pheochromocytoma and those at risk for sporadic pheochromocytoma had no known genetic predisposition to the disease and no previous history of pheochromocytoma. 6 subjects without pheochromocytoma who had "interfering substances" noted upon measurement of the metanephrine fraction were excluded. ‡ Mean age of pheochromocytoma patients in NIH study: 33 years for genetically predisposed patients and 47 for sporadic patients. Mean age of nonpheochromocytoma patients in NIH study: 38 for genetically predisposed patients, 47 for sporadic patients.