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Table 2 Demographic characteristics of subjects in included studies

From: A systematic review of the literature examining the diagnostic efficacy of measurement of fractionated plasma free metanephrines in the biochemical diagnosis of pheochromocytoma

Demographic characteristic

Mayo Clinic*

NIH

Vienna

Years of recruitment of patients

1999–2001

1994–2001

Unclear

Proportion of female gender of all patients

287/507 (57%)

475/858 (55%)

24/31 (77%)

Proportion of sporadic pheochromocytoma patients (%)

39/56 (70%)

138/214 (64%)

14/17 (82%)

Proportion of non-pheochromocytoma patients with no genetic predisposition to disease†

399/445 (90%)

305/644 (47%)

Unclear

Mean age, years (range) of all pheochromocytoma patients

49 (16–83)

33,47‡ (8–78)

46

Mean age, years (range) of all non-pheochromocytoma patients

52 (7–86)

38,47‡ (8–77)

44

  1. *Published Mayo Clinic data was supplemented with new data. † Subjects with sporadic pheochromocytoma and those at risk for sporadic pheochromocytoma had no known genetic predisposition to the disease and no previous history of pheochromocytoma. 6 subjects without pheochromocytoma who had "interfering substances" noted upon measurement of the metanephrine fraction were excluded. ‡ Mean age of pheochromocytoma patients in NIH study: 33 years for genetically predisposed patients and 47 for sporadic patients. Mean age of nonpheochromocytoma patients in NIH study: 38 for genetically predisposed patients, 47 for sporadic patients.