Ogg1 immunofluorescent staining in human pancreata. Ogg1 staining (green) and somatostatin (red), as a marker for islets of Langerhans, in normal human pancreata (A, C, E); and pancreata from type 2 diabetic subjects (B, D, F). Micrograph A is representative of an islet with no or very little Ogg1 staining; B of an islet with moderate staining intensity of 25% of the area; C, strong staining of 50% of the area; D, strong staining of 100% of the area; E, strong staining of 75% of the area; and F, strong staining of 100% of the area. Notably, the surrounding exocrine tissue is positive for Ogg1 at varying degrees (B and D vs. the rest). The micrographs were captured with identical camera settings. Original optical magnification 400×.