From: A clinical prediction score for diagnosing unilateral primary Aldosteronism may not be generalizable
Lateralized AVS | Nonlateralized AVS | P value | |
---|---|---|---|
n | 64 | 46 | |
Age, years | 49 [40,58] | 48 [39,55] | 0.69 |
BMI (kg/m2) | 29.0 [25.7,33.8] | 30.9 [25.5,33.7] | 0.89 |
Percentage of male subjects (%) | 39 (61%) | 20 (44%) | 0.11 |
Systolic BP at presentation (mm Hg) | 149 [136,161] | 145 [131,158] | 0.55 |
Diastolic BP at presentation (mm Hg) | 90 [81,100] | 91 [80,100] | 0.90 |
Initial plasma aldosterone (ng/dl) | 19.0 [14.7,29.4] | 13.9 [9.0,17.7] | 0.002 |
Aldosterone renin ratio (normal <15) | 128 [47,266] | 104 [50,142] | 0.10 |
Plasma renin activity (ng/mL/h) | 0.14 [0.1,0.32] | 0.11 [0.1,0.25] | 0.38 |
Initial serum K+ (mmmol/liter) | 2.9 [2.6,3.5] | 3.7 [3.2,3.8] | <0.0001 |
Serum potassium < 3.5 mmol/liter (%) mmmmmmolmmol/liter (%) | 49 (77) | 22 (46) | 0.002 |
eGFR (ml/min/1.73 m2) | 87.1 [67.8,96.5] | 80.5 [67.9,98.3] | 0.73 |
Adenoma ≥8 mm on CT (%) | 46 (72) | 16 (36) | <0.0001 |