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Table 5 Urinary concentrations of phthalate metabolites and bisphenol A in polycystic ovary syndrome (PCOS) case-patients and controls

From: Exploring the potential association between brominated diphenyl ethers, polychlorinated biphenyls, organochlorine pesticides, perfluorinated compounds, phthalates, and bisphenol a in polycystic ovary syndrome: a case–control study

Agents

 

Geometric mean concentration (μg/L)

Creatinine-adjusted geometric mean concentration (μg/g creatinine)

Phthalates

Phthalate metabolites measured

PCOS case-patients

PCOS control-patients

PCOS case-patients

PCOS control-patients

Butylbenzyl phthalate (BBzP)

Monobenzyl phthalate (mBzP)

4.7

9.0

7.5

11.7a

Di-n-butyl phthalate (DBP)

Mono-n-butyl phthalate (mBP)

15.3

24.8

17.7

23.2

Diethyl phthalate (DEP)

Monoethyl phthalate (mEP)

103.7

138.3

181.1

195.8

Di-isodecyl phthalate (DiDP)

Mono(carboxynonyl) phthalate (mCNP)

3.2

3.0

3.6

2.6

Di-isononyl phthalate (DiNP)

Mono(carboxyoctyl) phthalate (mCOP)

6.7

9.0

7.8

8.4

Di-n-octyl phthalate (DOP)

Mono-3-carboxypropyl phthalate (mCPP)

2.4

3.6

2.8

3.4

Di-2-ethylhexyl phthalate (DEHP)

Mono-2-ethyl-5-carboxypentyl phthalate (mECPP)

41.5

43.2

47.9

40.4

 

Mono-2-ethyl-5-hydroxyhexyl phthalate (mEHHP)

23.7

28.3

27.3

26.4

 

Mono-2-ethylhexyl phthalate (mEHP)

3.3

4.0

3.2

3.5

 

Mono-2-ethyl-5-oxohexyl phthalate (mEOHP)

14.0

17.4

16.2

16.3

Di-isobutyl phthalate (DiBP)

Mono-isobutyl phthalate (miBP)

6.0

8.7

7.0

8.2

Phenols

     

bisphenol A (BPA)

 

1.6

2.1

1.6

1.9

  1. ap = 0.02 where controls have higher mBzP urinary concentrations than case-patients.