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Table 3 Serum and lipid-adjusted concentrations of brominated diphenyl ethers, polychlorinated biphenyls, and persistent organic pesticides, and perfluorinated compounds in polycystic ovary syndrome (PCOS) case-patients and controls

From: Exploring the potential association between brominated diphenyl ethers, polychlorinated biphenyls, organochlorine pesticides, perfluorinated compounds, phthalates, and bisphenol a in polycystic ovary syndrome: a case–control study

  Geometric mean whole weight concentration (pg/g serum) Lipid-adjusted concentration (ng/g lipid)
Compounds Case-patients Controls Case-patients Controls
Brominated (Bi-) Diphenyl Ethers     
2,4,4′-tribromodiphenyl ether (PBDE28) 10.8 9.9 1.9 1.8
2,2′,4,4′-tetrabromodiphenyl ether (PBDE47) 144.5 148.6 24.9 26.5
2,2′,4.4′,5-pentabromodiphenyl ether (PBDE99) 27.5 28.8 4.7 5.1
2,2′,4,4′,6-pentabromodiphenyl ether (PBDE100) 27.8 29.8 4.8 5.3
2,2′,4,4′,5,5′-hexabromobiphenyl (BB153) 3.3 6.0 0.6 1.0a
2,2′,4,4′,5,5′-hexabromodiphenyl (PBDE153) 29.7 34.3 5.1 6.1
Polychlorinated Biphenyls     
2,2′,4,4′,5-pentaCB (PCB99) 10.8 12.8 1.9 2.3
2,3,3′,4,4′-pentaCB (PCB105) 3.8 3.8 0.7 0.7
2,3′,4,4′,5-pentaCB (PCB118) 15.6 15.6 2.7 2.8
2,2′,3,4′,5,5′-hexaCB (PCB146) 4.2 5.0 0.7 0.9
2,2′,4,4′,5,5′-hexaCB (PCB153) 38.6 47.2 6.7 8.4
2,3,3′,4,4′,5-hexaCB (PCB156) 4.3 5.4 0.7 1.0
2,2′,3,4,4′,5′-hexaCB (PCB138-158) 31.5 35.7 5.4 6.4
2,2′,3,3′,4,4′,5-heptaCB (PCB170) 9.9 12.0 1.7 2.1
2,2′,3,4,4′,5,5′-heptaCB (PCB180) 25.1 29.7 4.3 5.3b
2,2′,3,4,4′,5′,6-heptaCB (PCB183) 3.8 4.4 0.7 0.8
2,2′,3,4′,5,5′,6-heptaCB (PCB187) 7.1 9.2 1.2 1.7
2,2′,3,3′,4,5,6,6′-octaCB (PCB199) 4.0 5.3 0.7 0.9
2,2′,3,3′,4,4′,5,5′-octaCB (PCB 194) 0.7 1.1 0.7 1.1
2,2′,3,3′,4,4′,5′,6-octaCB and 2,2′,3,4,4′,5,5′,6-octaCB (PCB196_203) 4.6 6.2 0.8 1.1
Persistent pesticides     
Hexachlorobenzene (HCB) 53.9 51.2 9.2 9.1
β-Hexachlorocyclohexane (B-HCCH) 16.0 16.1 4.2 4.4
Oxychlordane 18.6 23.1 3.2 4.1
Trans-Nonachlor 29.6 31.9 5.1 5.7
2,2-Bis(4-chlorophenyl)-1, 1-dichloroethene (PP DDE) 1217.5 1397.2 210.2 248.7
2,2-Bis(4-chlorophenyl-1, 1, 1-trichloroethane (PP DDT) 19.0 18.1 3.3 3.2
Perfluorinated Compounds μg/L serum μg/L serum   
Perfluorooctanoate (PFOA) 4.1 2.3c   
Perfluorooctane sulfonate (PFOS) 8.2 4.9d   
Perfluorohexane sulfonate (PFHxS) 1.1 0.7   
Perfluorononanoate (PFNA) 1.2 0.9   
  1. ap = 0.02 where controls have higher BB153 levels than case-patients.
  2. bp = 0.04 where controls have higher PCB180 levels than case-patients.
  3. cp = 0.001 where case-patients have higher PFOA levels than controls.
  4. dp = 0.01 where case-patients have higher PFOS levels than controls.