Table 3 Serum and lipid-adjusted concentrations of brominated diphenyl ethers, polychlorinated biphenyls, and persistent organic pesticides, and perfluorinated compounds in polycystic ovary syndrome (PCOS) case-patients and controls
Geometric mean whole weight concentration (pg/g serum) | Lipid-adjusted concentration (ng/g lipid) | |||
|---|---|---|---|---|
Compounds | Case-patients | Controls | Case-patients | Controls |
Brominated (Bi-) Diphenyl Ethers | ||||
2,4,4′-tribromodiphenyl ether (PBDE28) | 10.8 | 9.9 | 1.9 | 1.8 |
2,2′,4,4′-tetrabromodiphenyl ether (PBDE47) | 144.5 | 148.6 | 24.9 | 26.5 |
2,2′,4.4′,5-pentabromodiphenyl ether (PBDE99) | 27.5 | 28.8 | 4.7 | 5.1 |
2,2′,4,4′,6-pentabromodiphenyl ether (PBDE100) | 27.8 | 29.8 | 4.8 | 5.3 |
2,2′,4,4′,5,5′-hexabromobiphenyl (BB153) | 3.3 | 6.0 | 0.6 | 1.0a |
2,2′,4,4′,5,5′-hexabromodiphenyl (PBDE153) | 29.7 | 34.3 | 5.1 | 6.1 |
Polychlorinated Biphenyls | ||||
2,2′,4,4′,5-pentaCB (PCB99) | 10.8 | 12.8 | 1.9 | 2.3 |
2,3,3′,4,4′-pentaCB (PCB105) | 3.8 | 3.8 | 0.7 | 0.7 |
2,3′,4,4′,5-pentaCB (PCB118) | 15.6 | 15.6 | 2.7 | 2.8 |
2,2′,3,4′,5,5′-hexaCB (PCB146) | 4.2 | 5.0 | 0.7 | 0.9 |
2,2′,4,4′,5,5′-hexaCB (PCB153) | 38.6 | 47.2 | 6.7 | 8.4 |
2,3,3′,4,4′,5-hexaCB (PCB156) | 4.3 | 5.4 | 0.7 | 1.0 |
2,2′,3,4,4′,5′-hexaCB (PCB138-158) | 31.5 | 35.7 | 5.4 | 6.4 |
2,2′,3,3′,4,4′,5-heptaCB (PCB170) | 9.9 | 12.0 | 1.7 | 2.1 |
2,2′,3,4,4′,5,5′-heptaCB (PCB180) | 25.1 | 29.7 | 4.3 | 5.3b |
2,2′,3,4,4′,5′,6-heptaCB (PCB183) | 3.8 | 4.4 | 0.7 | 0.8 |
2,2′,3,4′,5,5′,6-heptaCB (PCB187) | 7.1 | 9.2 | 1.2 | 1.7 |
2,2′,3,3′,4,5,6,6′-octaCB (PCB199) | 4.0 | 5.3 | 0.7 | 0.9 |
2,2′,3,3′,4,4′,5,5′-octaCB (PCB 194) | 0.7 | 1.1 | 0.7 | 1.1 |
2,2′,3,3′,4,4′,5′,6-octaCB and 2,2′,3,4,4′,5,5′,6-octaCB (PCB196_203) | 4.6 | 6.2 | 0.8 | 1.1 |
Persistent pesticides | ||||
Hexachlorobenzene (HCB) | 53.9 | 51.2 | 9.2 | 9.1 |
β-Hexachlorocyclohexane (B-HCCH) | 16.0 | 16.1 | 4.2 | 4.4 |
Oxychlordane | 18.6 | 23.1 | 3.2 | 4.1 |
Trans-Nonachlor | 29.6 | 31.9 | 5.1 | 5.7 |
2,2-Bis(4-chlorophenyl)-1, 1-dichloroethene (PP DDE) | 1217.5 | 1397.2 | 210.2 | 248.7 |
2,2-Bis(4-chlorophenyl-1, 1, 1-trichloroethane (PP DDT) | 19.0 | 18.1 | 3.3 | 3.2 |
Perfluorinated Compounds | μg/L serum | μg/L serum | ||
Perfluorooctanoate (PFOA) | 4.1 | 2.3c | ||
Perfluorooctane sulfonate (PFOS) | 8.2 | 4.9d | ||
Perfluorohexane sulfonate (PFHxS) | 1.1 | 0.7 | ||
Perfluorononanoate (PFNA) | 1.2 | 0.9 | ||