Table 1 Laboratory results (follow up period)
From: A novel mutation in calcium-sensing receptor gene associated to hypercalcemia and hypercalciuria
Patient I:1 | ||||
|---|---|---|---|---|
First values | 1 year follow-up (after cinacalcet) | 2 years follow-up (no specific therapy) | 4 years follow-up (no specific therapy) | |
s-Ca total (correct) (n.v. 8.8-10.6) | 11.6 mg/dl | 10.9 mg/dl | 12.96 mg/dl | 11.8 mg/dl |
s-PO4 (n.v. 2.7-4.5) | 3 mg/dl | 2.5 mg/dl | 2.2 mg/dl | 2.4 mg/dl |
s-Creatinine (n.v. 0.2-1.2) | 1.08 mg/dl | 1.12 mg/dl | 1.31 mg/dl | 1.19 mg/dl |
s-PTH (n.v. 5–40) | 25.7 pg/ml | 33 mg/dl | 19.4 mg/dl | 25.4 mg/dl |
25(OH)vitamin D (n.v. 30–100) | 16 ng/ml | 16 ng/ml | 40.7 ng/ml | - |
U Ca (n.v. < 4 mg/Kg) | - | 658 mg/24 h | 315 mg/24 h | 325 mg/24 h |
Cr Clearance (n.v. 70– 120 ml/min) | - | 67 ml/min | 55 ml/min | 61 ml/min |
Ca/Cr ratio | - | 0.041 | 0.031 | 0.030 |