BMC Endocrine Disorders

Table 1 Age-related characteristics, bone turnover markers and T-scores at various skeletal sites

From: Age-related bone turnover markers and osteoporotic risk in native Chinese women

Marker	Age (years)
Marker	20–29 (n = 124)	30–39 (n = 141)	40–49 (n = 238)	50–59 (n = 229)	60–69 (n = 133)	≥70 (n = 26)
Height (cm)	158 ± 5.6^b	157 ± 5.3^b	155 ± 5.1	154 ± 4.6	151 ± 5.0	152 ± 4.6
Weight (kg)	50.1 ± 6.5^b	54.3 ± 7.4	57.5 ± 8.1	56.1 ± 8.5	54.5 ± 8.7	54.4 ± 9.3
BMI (kg/m ² )	20.2 ± 2.3^b	22.0 ± 2.5^b	23.9 ± 3.0	23.7 ± 3.3	23.7 ± 3.2	23.7 ± 3.7
MSU-Cr (mmol/L)	11.4 ± 5.1^b	11.0 ± 5.0^b	8.8 ± 4.7	7.7 ± 4.3	7.8 ± 4.4	8.9 ± 5.2
BAP (U/L) ^a	16.0 ± 1.3	15.5 ± 1.4	22.0 ± 1.5^c	32.1 ± 1.4^d	29.1 ± 1.4	25.5 ± 1.4
OC (μg/L) ^a	7.3 ± 1.5	4.7 ± 1.6	5.7 ± 1.8^c	10.6 ± 1.6^d	10.4 ± 1.6	10.2 ± 1.4
sNTX (nmol/L) ^a	13.9 ± 1.3	13.0 ± 1.3	13.2 ± 1.5	16.2 ± 1.5^d	18.0 ± 1.5	19.0 ± 1.3
sCTX (mg/L) ^a	3.7 ± 1.4	2.4 ± 1.6	2.6 ± 1.9	4.1 ± 1.6^d	4.1 ± 1.6	4.9 ± 1.6
uNTX (nM BCE/mM Cr) ^a	33.3 ± 1.6	24.6 ± 1.7	33.3 ± 2.2^c	60.3 ± 2.2^d	49.8 ± 2.2	36.4 ± 1.9
uCTX (μg/mM Cr) ^a	167 ± 1.7	85.1 ± 3.0	117 ± 2.6^c	244 ± 2.2^d	235 ± 2.1	193 ± 2.1
uDPD (nM/mM Cr) ^a	6.1 ± 1.4	4.2 ± 1.8	5.0 ± 1.8^c	6.3 ± 1.6^d	6.1 ± 1.7	5.9 ± 1.6
PA T-score	0.0 ± 0.8	0.1 ± 0.9	−0.2 ± 1.1	−1.2 ± 1.1^d	−2.0 ± 1.0^e	−2.1 ± 1.0^e
FN T-score	−0.1 ± 1.1	−0.1 ± 1.2	−0.2 ± 1.2	−1.1 ± 1.2^d	−2.0 ± 1.0^e	−2.4 ± 1.0^e
Hip T-score	0.1 ± 0.9	0.1 ± 0.9	0.0 ± 1.0	−0.7 ± 0.9^d	−1.5 ± 0.8^e	−1.8 ± 1.0^e

Abbreviations: BMI body mass index, MSU Cr-morning second urinary creatinine, BAP bone-specific alkaline phosphatase, OC osteocalcin, sNTX serum cross-linked N-terminal telopeptides of type I collagen (NTX), sCTX serum cross-linked C-terminal telopeptides of type I collagen (CTX), uNTX urinary NTX, uCTX urinary CTX, uDPD urinary deoxypyridinoline, Cr reatinine, BCE bone collagen equivalents, PA posteroanterior spine, FN femoral neck, Hip total hip. ^aValues are expressed as geometric mean ± SD. ^b P = 0.005–0.000 compared with various age groups of ≥40 years. ^c P = 0.032–0.000 compared with the age groups of 30–39 years. ^d P = 0.025–0.000 compared with the age groups of 30–39 and 40–49 years. ^e P = 0.000 compared with various age groups of <60 years.

Back to article page

ISSN: 1472-6823

Contact us

General enquiries: journalsubmissions@springernature.com