Table 3 PAM SNP genotype relationships with serum PHM and PAL activity and metals
SNP | rs32680 | rs249496 | rs10038600 | rs7722485 | rs11952361 | rs10515341 | rs17296280 | rs5855 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Geno-type | CC (73) | CT (39) | TT (8) | CC (18) | CG (48) | GG (54) | GG (50) | GT (52) | TT (18) | AA (64) | AG (43) | GG (13) | AA (60) | AG (45) | GG (15) | AA (13) | AG (46) | GG (61) | AA (61) | AC (47) | CC (12) | AA (60) | AG (47) | GG (13) |
PHM | 5.57±0.97§ | 5.69±1.25§ | 4.68±1.13§†‡ | 5.54±1.02 | 5.56±1.03 | 5.54±1.19 | 5.31±1.05†‡ | 5.78±1.14§ | 5.56±1.00 | 5.58±1.24 | 5.58±0.91 | 5.32±0.96 | 5.64±1.01 | 5.60±1.09 | 5.03±1.36‡ | 4.74±0.99§†‡ | 5.69±1.16§ | 5.62±1.00§ | 5.55±0.97 | 5.66±1.21 | 5.11±1.20 | 5.65±1.03 | 5.54±1.06 | 5.10±1.43 |
PAL | 19.3±4.2§ | 19.7±4.6§ | 15.9±4.7§†‡ | 20.2±5.0 | 19.6±3.9 | 18.5±4.6 | 19.2±4.5 | 19.4±4.6 | 18.6±3.7 | 18.7±4.6 | 19.8±3.8 | 19.6±5.3 | 19.3±4.1 | 19.5±5.0 | 18.0±4.0 | 17.1±3.7 | 19.5±5.0 | 19.4±4.1 | 19.3±4.2 | 19.4±4.7 | 17.8±4.7 | 19.4±4.2 | 19.4±4.8 | 17.7±4.1 |
PHM/PAL | 0.30±0.08 | 0.30±0.07 | 0.32±0.11 | 0.29±0.08 | 0.29±0.07 | 0.31±0.08 | 0.29±0.08 | 0.31±0.08 | 0.31±0.09 | 0.31±0.09 | 0.29±0.06 | 0.29±0.10 | 0.31±0.08 | 0.30±0.07 | 0.29±0.09 | 0.29±0.09 | 0.30±0.07 | 0.30±0.08 | 0.30±0.08 | 0.30±0.07 | 0.30±0.09 | 0.30±0.08 | 0.30±0.07 | 0.30±0.09 |
Cp | 186±44 | 194±49 | 192±49 | 207±47§ | 195±43 | 178±46§‡ | 196±51§ | 192±41§ | 160±32§†‡ | 182±45 | 197±49 | 198±34 | 183±38† | 202±51§ | 175±52 | 168±50† | 198±48§ | 186±42 | 190±44 | 191±49 | 173±41 | 186±38 | 195±53 | 180±51 |
Cu | 996±209 | 1013±256 | 975±302 | 1076±218§ | 1027±236 | 951±221§‡ | 1045±254§ | 984±223 | 921±144§‡ | 981±226 | 1020±248 | 1030±188 | 989±212 | 1020±225 | 986±314 | 946±308 | 1023±232 | 994±212 | 989±195 | 1020±267 | 980±256 | 998±210 | 1002±228 | 1003±330 |
Zn | 846±284 | 911±263 | 828±199 | 879±273 | 853±283 | 872±268 | 903±305 | 834±237 | 853±274 | 871±250 | 866±321 | 839±213 | 840±228 | 894±339 | 884±216 | 885±233 | 899±332 | 837±229 | 822±225 | 909±331 | 921±217 | 842±227 | 885±336 | 906±213 |
Cu/Zn | 1.26±0.36 | 1.17±0.37 | 1.18±0.23 | 1.31±0.39 | 1.26±0.29 | 1.17±0.40 | 1.23±0.35 | 1.24±0.37 | 1.16±0.37 | 1.19±0.38 | 1.26±0.36 | 1.27±0.24 | 1.22±0.30 | 1.25±0.44 | 1.14±0.32 | 1.09±0.29 | 1.24±0.42 | 1.24±0.32 | 1.26±0.34 | 1.20±0.39 | 1.09±0.29 | 1.23±0.30 | 1.24±0.43 | 1.13±0.34 |
Cu/Cp | 5.51±1.17 | 5.31±0.89 | 5.08±1.00 | 5.33±1.05 | 5.38±1.05 | 5.48±1.12 | 5.43±0.97 | 5.22±1.05§ | 5.94±1.30† | 5.51±1.05 | 5.32±1.19 | 5.25±0.75 | 5.54±1.17 | 5.160.89 | 5.701.09 | 5.70±1.17 | 5.24±0.88 | 5.50±1.18 | 5.36±1.14 | 5.43±1.00 | 5.71±1.02 | 5.50±1.17 | 5.27±0.95 | 5.57±1.07 |