Contrasting effects of preexisting hyperglycemia and higher body size on hospital mortality in critically ill patients: a prospective cohort study

Table 1 Clinical and laboratory characteristics according to survival

	Survivors	Nonsurvivors	P
	(n = 113)	(n = 86)	P
Age (years)	56 ± 17.4	61 ± 17	0.052
Males	65 (57. 5)	46 (53.5)	0.570
Days in hospital before ICU admission	2.5 (1–8)	6 (1–16)	<0.001
APACHE II	17.6 ± 7.9	24.8 ± 7.8	<0.001
SOFA	5 (2– 9)	8 (6 –13)	<0.001
Comorbidities
COPD	20 (18)	12 (14)	0.443
CHF	12 (10.8)	9 (10.5)	0.938
HIV	6 (5.4)	7 (8.1)	0.443
Body mass index (kg/m²)	27.2 ± 7.3	24.7 ± 5	0.031
History of DM	26 (23)	24 (27.9)	0.430
Glucose tolerance			0.359
Normal	51 (45.1)	41 (47.7)
Prediabetes	40 (35.4)	23 (26.7)
Diabetes	22 (19.5)	22 (25.6)
HbA_1c (%)	5.7 (5.3–6.3)	5.8 (5.2–6.5)	0.729
Serum glucose (mg/dL)	122 (99–160)	120 (95–167)	0.909
Lactate (mg/dL)	9.0 (6.3–15.3)	18 (0–35)	<0.001
C-reactive protein (mg/dL)	87 (27.5–150.4)	102 (44 –234)	0.067
Mechanical ventilation	69 (61.1)	68 (79.1)	0.008
Hemodialysis	15 (13.3)	30 (34.9)	<0.001
Vasopressor support	39 (34.5)	64 (74.4%)	<0.001

Data are expressed as mean ± standard deviation, median (interquartile range), or n (%). COPD, chronic obstructive pulmonary disease; CHF, congestive heart failure; HIV, human immunodeficiency virus. To convert glucose from mg/dl to mmol/L, multiply by the factor 0.005. To convert lactate from mg/dL to mmol/L, multiply by the factor 0.111.

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