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Table 2 Association of metabolic syndrome related traits with thyroid function index in the SAFHS participants

From: Increased waist circumference is independently associated with hypothyroidism in Mexican Americans: replicative evidence from two large, population-based studies

Metabolic syndrome-related trait

All subjects

Males

Females

 

Unadjusted

Adjusted†

Unadjusted

Adjusted††

Unadjusted

Adjusted††

 

β

p

β

p

β

p

β

p

β

P

β

p

Fasting glucose

0.08

0.03

-0.02

0.62

0.07

0.19

0.01

0.91

0.07

0.14

-0.03

0.53

2-hour glucose

0.14

<0.0001

0.05

0.15

0.16

<0.01

0.11

0.05

0.09

0.06

-0.01

0.82

Fasting insulin

0.04

0.27

0.00

0.96

0.03

0.62

0.01

0.78

0.03

0.52

-0.01

0.77

2-hour insulin

0.08

0.02

0.04

0.22

0.07

0.18

0.04

0.43

0.07

0.13

0.03

0.47

HOMA-IR

0.06

0.12

0.00

0.94

0.04

0.41

0.02

0.78

0.05

0.33

-0.02

0.68

HOMA-β

-0.07

0.06

0.02

0.58

-0.05

0.38

0.01

0.86

-0.06

0.1763

0.04

0.47

WC

0.19

<0.0001

0.13

<0.001

0.12

0.04

0.08

0.18

0.20

<0.0001

0.14

0.001

BMI

0.15

<0.0001

0.11

<0.01

0.04

0.45

0.02

0.76

0.18

<0.0001

0.13

<0.01

WHR

0.15

<0.0001

0.09

0.01

0.23

<0.001

0.20

<0.01

0.16

0.0001

0.10

0.02

Total serum cholesterol

0.12

0.0001

0.06

0.06

0.08

0.10

0.07

0.19

0.11

0.0101

0.03

0.46

Serum triglycerides

0.15

<0.0001

0.08

0.02

0.12

0.02

0.09

0.07

0.14

<0.01

0.07

0.14

Serum HDL cholesterol

0.05

0.11

0.06

0.06

0.05

0.32

0.07

0.15

0.02

0.67

0.02

0.69

Central obesity

0.30

<0.0001

0.20

<0.01

0.16

0.14

0.13

0.26

0.33

0.0001

0.20

0.02

Raised triglycerides

0.16

0.02

0.05

0.42

0.13

0.19

0.09

0.39

0.19

0.03

0.06

0.49

Low HDL cholesterol

-0.02

0.81

-0.05

0.46

0.12

0.28

0.08

0.49

-0.11

0.20

-0.11

0.17

High blood pressure

-0.25

<0.01

-0.05

0.61

-0.10

0.44

0.06

0.65

-0.26

0.01

-0.06

0.61

Type 2 diabetes

0.15

0.04

-0.04

0.60

0.14

0.22

-0.01

0.95

0.15

0.14

-0.04

0.70

Metabolic syndrome

0.27

<0.0001

0.16

0.02

0.28

0.02

0.25

0.04

0.24

<0.01

0.11

0.24

  1. †Adjusted for age, age2, sex, age x sex interaction and age2 x sex interaction; ††, adjusted for age and age2; numbers in bold face indicate statistically significant associations after correcting for multiple testing.