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Table 1 Serum ionized and total calcium in patients with idiopathic hypoparathyroidism and controls during menstruation and their relationship with hypocalcemic symptoms

From: Menstruation associated hypocalcemic symptoms and serum calcium in patients with idiopathic hypoparathyroidism

 

Patients with idiopathic hypoparathyroidism

Healthy women

Study points

Menstrual cycle 1

Menstrual cycle 2

Menstrual cycle 1

Menstrual cycle 2

 

a

b

c

d

e

f

g

h

a

b

c

d

e

f

g

h

Serum ionized Ca (mmol/l)

1*

1.04

1.12

1.11

0.92

0.92

0.90

0.91

0.93

1.09

1.20

1.16

1.13

1.19

1.14

1.13

1.12

2

0.78

0.77

0.88

0.81

0.91

0.84

0.88

0.91

1.19

1.14

1.13

1.17

1.19

1.13

1.12

1.16

3*

0.85

-

0.82

0.97

0.86

0.86

-

0.85

1.12

1.17

1.17

1.16

1.11

1.15

1.17

1.09

4

0.96

0.94

1.01

1.06

0.98

0.92

-

0.90

1.12

1.12

1.15

1.17

-

-

1.07

1.13

5*

0.91

0.83

0.82

1.15

 

0.82

0.86

0.91

1.13

1.18

1.17

1.14

1.17

1.10

1.13

1.12

6

1.04

1.05

1.05

1.04

1.08

1.09

1.05

1.03

1.12

1.13

1.17

1.18

1.09

1.13

1.12

1.15

7

1.04

0.96

0.92

1.01

1.01

1.04

-

0.91

1.17

1.14

1.17

1.16

1.11

1.09

1.12

1.19

8

1.13

1.16

1.13

1.16

1.14

1.11

1.09

1.12

1.16

1.17

1.14

1.15

1.16

1.18

1.15

1.21

9*

1.07

1.06

1.00

1.04

0.95

0.89

0.93

0.86

-

-

-

-

-

-

-

-

10*

0.84

0.89

0.93

0.90

-

-

-

-

-

-

-

-

-

-

-

-

11

0.83

0.94

0.93

0.77

0.85

0.79

0.77

0.77

-

-

-

-

-

-

-

-

12*

0.79

-

0.84

0.82

0.94

0.92

-

0.85

-

-

-

-

-

-

-

-

Serum total Ca (mmol/l)

1*

2.05

2.00

1.98

2.13

1.93

1.88

2.00

-

2.43

2.18

2.30

2.30

2.38

2.30

2.30

2.25

2

2.05

1.90

1.78

1.52

2.08

1.68

1.80

1.95

2.38

2.40

2.33

2.30

2.33

2.55

2.45

2.35

3*

1.70

 

1.83

1.70

1.78

1.78

-

1.73

2.20

2.28

 

2.53

2.48

2.43

2.38

2.35

4

2.05

2.05

1.98

2.25

1.98

1.90

-

2.40

2.33

2.30

2.30

2.25

-

-

2.25

2.33

5*

1.88

1.70

1.75

2.50

 

1.65

1.70

1.95

2.23

2.40

2.30

2.25

2.50

2.35

2.30

2.35

6

1.93

2.28

2.15

2.15

2.03

2.20

2.10

2.10

2.33

2.48

2.38

1.83

2.30

2.40

2.63

2.30

7

1.88

1.80

2.03

2.08

1.95

2.13

-

1.83

2.40

2.35

2.30

2.25

2.23

2.28

2.23

2.58

8

2.25

1.98

2.00

2.08

1.90

2.03

2.08

2.18

2.55

2.40

2.48

2.48

-

-

-

2.38

9*

2.15

2.13

2.10

2.15

1.88

1.85

1.95

1.78

-

-

-

-

-

-

-

-

10*

1.70

1.73

1.90

1.80

-

-

-

-

-

-

-

-

-

-

-

-

11

1.73

1.85

1.85

1.63

1.68

1.48

1.70

1.55

-

-

-

-

-

-

-

-

12*

1.63

 

1.78

1.90

1.85

1.88

-

1.73

-

-

-

-

-

-

-

-

  1. Cells with bold digits indicates point during menstrual cycles when patients recorded hypocalcemic symptoms. *Patients with past history of hypocalcemic symptoms during menstruations.