Table 1 Baseline characteristics of PAD (ABI ≤ 0.9) and non–PAD (1.3 ≥ ABI > 0.9) diabetic patients
Variables | PAD n = 138 | No-PAD n = 369 | p value |
|---|---|---|---|
Male/Female, n | 103/35 | 260/109 | 0.414 |
Age (years) | 60.9 ± 8.2 | 59.8 ± 7.7 | 0.161 |
BMI | 20.22 ± 2.79 | 20.18 ± 2.66 | 0.882 |
Duration of diabetes (year) | 6.3 ± 3.7 | 5.8 ± 3.2 | 0.035 |
ABI | 0.78 ± 0.11 | 1.09 ± 0.12 | 0.000 |
Systolic blood pressure (mmHg) | 132.4 ± 12.7 | 131.7 ± 11.5 | 0.554 |
Diastolic blood pressure (mmHg) | 77.7 ± 6.7 | 78.1 ± 7.4 | 0.579 |
HbA1c (%) | 7.9 ± 0.9 | 7.6 ± 0.8 | 0.034 |
Serum creatinine (μmol/l) | 91.4 ± 7.2 | 90.9 ± 6.6 | 0.418 |
Serum uric acid (μmol/l) | 234.7 ± 34.4 | 229.4 ± 32.7 | 0.105 |
UACR (μg/mg) | 72.4 ± 27.2 | 68.5 ± 25.4 | 0.132 |
Total cholesterol (mmol/l) | 4.87 ± 1.04 | 4.76 ± 1.11 | 0.313 |
Triglycerides (mmol/l) | 1.24 ± 0.32 | 1.21 ± 0.27 | 0.291 |
High-density lipoprotein cholesterol (mmol/l) | 1.09 ± 0.21 | 1.12 ± 0.22 | 0.167 |
Low-density lipoprotein cholesterol (mmol/l) | 2.44 ± 0.43 | 2.39 ± 0.38 | 0.204 |
C-reactive protein (mg/l) | 5.3 ± 1.1 | 5.2 ± 1.1 | 0.432 |
Fibrinogen (mg/dl) | 3.21 ± 0.87 | 3.14 ± 0.79 | 0.388 |
Left ventricular ejection fraction (%) | 61.7 ± 4.6 | 62.3 ± 5.1 | 0.227 |
E/A | 1.22 ± 0.24 | 1.25 ± 0.26 | 0.547 |
BNP (median and interquartile range) (pg/ml) | 78 (4.5–529) | 71 (5.0–497) | 0.001 |
Hypertension, n (%) | 56 (40.58) | 137 (37.13) | 0.542 |
Hyperlipidemia, n (%) | 58 (42.03) | 129 (34..96) | 0.142 |
Current smoking, n (%) | 55 (39.86) | 141 (38.21) | 0.814 |
RAAS blockade, n (%) | 32 (23.19) | 81 (21.95) | 0.859 |
Calcium channel blockers, n (%) | 21 (15.22) | 62 (16.80) | 0.768 |
Statin therapy, n (%) | 27 (19.57) | 81 (21.95) | 0.644 |
Aspirin therapy, n (%) | 33 (23.91) | 102 (27.64) | 0.464 |