2006 | 2012 | p | |
---|---|---|---|
Glucose-lowering (all patients) | 390.7 [363.5-418.0] | 612.4 [586.5-638.2] | < 0.001 |
Glucose-lowering (only treated patients) | 405.3 [377.6-433.1] | 621.1 [595.1-647.1] | < 0.001 |
OAD only | 324.9 [297.0-352.9] | 504.5 [476.3-532.7] | < 0.001 |
Insulin | 553.8 [501.6-606.0] | 763.8 [720.6-807.0] | < 0.001 |
Excluding incretins | 405.3 [501.6-606.0] | 508.0 [474.7-541.3] | < 0.001 |
Excluding incretins & adjusting for insulin analog use | 442.4 [415.2-469.6] | 463.2 [431.5-495.0] | 0.34 |
Antihypertensive (all patients) | 285.3 [270.6-300.1] | 255.2 [241.1-269.2] | 0.004 |
Antihypertensive (only treated patients) | 371.5 [356.0-387.1] | 318.7 [304.7-332.7] | < 0.001 |
Lipid-lowering (all patients) | 357.3 [335.0-379.5] | 361.0 [339.9-382.1] | 0.81 |
Lipid-lowering (only treated patients) | 571.8 [547.2-596.4] | 449.9 [429.5-450.3] | < 0.001 |
Antiplatelet (all patients) | 89.0 [75.8-102.1] | 78.1 [65.6-90.7] | 0.25 |
Antiplatelet (only treated patients) | 169.8 [146.2-193.4] | 146.4 [124.2-168.5] | 0.16 |
Total | 1122.3 [1078.1-1166.5] | 1306.7 [1264.6-1348.7] | < 0.001 |