Efficacy of alogliptin in type 2 diabetes treatment: a meta-analysis of randomized double-blind controlled studies

Table 1 Characteristic of studies included in this Meta-analysis, 2012

Authors	Year	Country	Duration	Medication before recruitment	Group1: alogliptin 12.5 mg +	Group2: alogliptin 25 mg +	Group 3 (controls)
Rosenstock et al., Study 1[13]	2009	Multiple	26wks	Insulin ± metformine	Alone	Alone	Placebo
Bosi et al.,[17]	2011	Multiple	52 wks	Metformine + pioglitazone	--	Metformine + pioglitazone	Metformine + pioglitazone
Nauck et al.,[18]	2009	Multiple	26wks	Metformin	Metformin	Metformine	Metformine + placebo
Kaku et al.,[23]	2011	Japan	12wks	Pioglitazone + diet + exercise	Pioglitazone	Pioglitazone	Piogitazone + placebo
Seino et al., Study 1[24]	2011	Japan	12wks	Diet +exercise	Alone	Alone	placebo
Pratley et al., Study 1[19]	2009	Multiple	26wks	TZD ± metformin or sulfonylureas	Pioglitazone	Pioglitazone	Pioglitazone
Pratley et al., Study2[20]	2009	Multiple	26wks	Sulfonylureas	Alone	Alone	Placebo
Defronzo et al.,[21]	2008	Multiple	26wks	Diet +exercise	Alone	Alone	Placebo
Rosenstock et al., Study 2[22]	2010	Multiple	26wks	Diet +exercise	Pioglitazone	Pioglitazone	Pioglitazone
Seino et al., Study 2[25]	2011	Japan	12wks	α-glucosidase inhibitor +diet	Voglibose	Voglibose	Voglibose

ISSN: 1472-6823