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Table 3 Hazard ratio (HR) of diabetes by quartiles of anthropometrical indices in men and women from the Spanish EPIC (European Prospective Investigation into Cancer and Nutrition) cohort

From: Risk of type 2 diabetes according to traditional and emerging anthropometric indices in Spain, a Mediterranean country with high prevalence of obesity: results from a large-scale prospective cohort study

 

Men

Women

 

Py

Cases

HR1

95% CI

HR2

95% CI

Py

Cases

HR1

95% CI

HR2

95% CI

Body mass index

            

Q1

43152

135

1

 

1

 

73322

52

1

 

1

 

Q2

43115

211

1.57

1.27 - 1.97

1.58

1.25 - 2.00

73311

132

1.51

1.08 - 2.11

1.26

0.90 - 1.77

Q3

42155

343

2.02

1.63 - 2.50

2.07

1.64 - 2.61

71690

331

2.89

2.12 - 3.95

2.11

1.52 - 2.93

Q4

40657

583

2.57

2.08 - 3.16

2.68

2.05 - 3.50

69564

726

4.14

3.04 - 5.64

2.48

1.73 - 3.57

Waist circumference

            

Q1

43948

118

1

 

1

 

79543

43

1

 

1

 

Q2

42483

230

1.58

1.25 - 1.99

1.49

1.18 - 1.90

72348

137

2.19

1.52 - 3.14

2.02

1.40 - 2.91

Q3

42502

353

1.92

1.54 - 2.40

1.74

1.37 - 2.22

69726

320

4.02

2.85 - 5.68

3.47

2.44 - 4.95

Q4

40146

571

2.32

1.86 - 2.86

1.93

1.46 - 2.55

66272

741

5.93

4.21 - 8.36

4.57

3.12 - 6.68

Hip circumference

            

Q1

42690

197

1

 

1

 

75803

100

1

 

1

 

Q2

44831

273

1.13

0.93 - 1.38

1.00

0.82 - 1.23

71293

192

1.56

1.21 - 2.02

1.24

0.96 - 1.61

Q3

40094

317

1.49

1.23 - 1.80

1.21

0.98 - 1.49

74551

335

1.98

1.56 - 2.52

1.24

0.96 - 1.60

Q4

41464

485

1.49

1.24 - 1.79

0.99

0.78 - 1.27

66241

614

2.50

1.97 - 3.17

1.00

0.73 - 1.35

Waist-to-hip ratio

            

Q1

49640

170

1

 

1

 

79106

80

1

 

1

 

Q2

38989

226

1.28

1.04 - 1.57

1.17

0.95 - 1.45

77254

208

1.59

1.21 - 2.10

1.50

1.14 - 1.98

Q3

47330

450

1.65

1.37 - 2.00

1.48

1.22 - 1.80

69546

337

2.27

1.74 - 2.97

1.98

1.52 - 2.60

Q4

33121

426

1.63

1.34 - 1.99

1.30

1.05 - 1.60

61983

616

3.18

2.46 - 4.12

2.67

2.06 - 3.47

Waist-to-height ratio

            

Q1

43815

105

1

 

1

 

73889

30

1

 

1

 

Q2

43545

224

1.53

1.20 - 1.96

1.48

1.15 - 1.89

73835

132

2.91

1.92 - 4.41

2.79

1.76 - 4.06

Q3

41515

365

2.05

1.62 - 2.59

1.91

1.50 - 2.42

71746

314

5.00

3.34 - 7.49

4.54

2.79 - 6.40

Q4

40204

578

2.32

1.84 - 2.93

2.07

1.60 - 2.69

68418

765

7.91

5.30 - 11.82

6.80

4.45 - 10.39

  1. Py: person-years, HR: hazard ratio, CI: confidence interval.
  2. 1 Models stratified by centre, age, and follow-up time, and adjusted by total energy intake, plausibility of energy reporting, alcohol intake, smoking status, educational level and recreational physical activity.
  3. 2 Multivariable models mutually adjusted by height, weight, and waist and hip circumferences, as applicable. Covariates, total energy intake, plausibility of energy reporting, alcohol intake, smoking status, educational level, physical activity, and menopausal status (women). Models were stratified by centre, age, and follow-up time.
  4. Cut-off points,
  5. Body mass index (kg/m2), 26.12 (Q1-Q2), 28.10 (Q2-Q3), 30.34 (Q3-Q4) [men]; 24.64 (Q1-Q2), 27.37 (Q2-Q3), 30.74 (Q3-Q4) [women].
  6. Waist circumference (cm), 93.0 (Q1-Q2), 98.8 (Q2-Q3), 104.5 (Q3-Q4) [men]; 79.0 (Q1-Q2), 86.0 (Q2-Q3), 94.0 (Q3-Q4) [women].
  7. Hip circumference (cm), 100.5 (Q1-Q2), 104.5 (Q2-Q3), 108.8 (Q3-Q4) [men]; 99.0 (Q1-Q2), 104.5 (Q2-Q3), 111.0 (Q3-Q4) [women].
  8. Waist-to-hip ratio, 0.91 (Q1-Q2), 0.94 (Q2-Q3), 0.98 (Q3-Q4) [men]; 0.78 (Q1-Q2), 0.82 (Q2-Q3), 0.86 (Q3-Q4) [women].
  9. Waist-to-height ratio, 0.55 (Q1-Q2), 0.58 (Q2-Q3), 0.62 (Q3-Q4) [men]; 0.50 (Q1-Q2), 0.55 (Q2-Q3), 0.60 (Q3-Q4) [women].
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BMC Endocrine Disorders

ISSN: 1472-6823

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