Reducing resistance to treatment, through group intervention, improves clinical measurements in patients with type 2 diabetes

Valinsky, Liora; Mishali, Moshe; Endevelt, Ronit; Preiss, Rachel; Dopelt, Keren; Heymann, Anthony D

doi:10.1186/1472-6823-13-61

Table 4 Results of the linear mixed models for resistance to treatment by study groups and time

From: Reducing resistance to treatment, through group intervention, improves clinical measurements in patients with type 2 diabetes

	Total resistance		Despair		Difficulty		Therapy		Emotions
HbA1C/P value at baseline ^α	0.101		0.968		0. 821		0.335		0.912
	Estimate ^†	P value	Estimate	P value	Estimate	P value	Estimate	P value	Estimate	P value
Group1 T2-T1	-0.39	0.001	-0.40	0.011	-0.49	0.002	-0.21	0.371	-0.38	0.005
T3-T1	-0.40	0.001	-0.59	0.001	-0.41	0.022	-0.09	0.700	-0.51	0.003
Group 0 T2-T1	-0.73	0.009	-0.48	0.118	-0.40	0.152	-0.78	0.002	-0.42	0.127
T3-T1	-0.69	0.013	-0.08	0.783	-0.39	0.174	-0.70	0.038	-0. 27	0.352
BPS/P value at baseline	0.999		0.432		0.594		0.616		0.083
Group1 T2-T1	-2.14	0.240	-3.75	0.113	-4.64	0.047	-3.60	0.181	-235	0.241
T3-T1	-4.19	0.031	--1.97	0.460	-5.00	0.067	-6.64	0.026	-2.48	0.305
Group 0 T2-T1	-4.59	0.124	-2.26	0.508	-5.62	0.059	-6.29	0.071	-7.16	0.011
T3-T1	-0.38	0.901	-1.16	0.745	-2.37	0.466	-5.34	1.35	-4.40	0.161
BPD/P value at baseline	0.989		0.091		0.520		0.445		0.665
	Total Resistance		despair		Difficulty		Therapy		Emotions
Group1 T2-T1	-1.40	0.185	-2.26	0.088	-2.69	0.037	-3.11	0.054	-2.20	0.049
T3-T1	-4.30	<0.001	-5.18	0.001	-5.81	<0.001	-5.16	0.004	-3.85	0.005
Group 0 T2-T1	-2.33	0.193	0.12	0.950	-1.58	0.367	-0.06	0.974	-2.31	0.174
T3-T1	-3.19	0.090	-1.27	0.539	-2.49	0.193	-3.94	0.068	-3.81	0.041
BMI/P value at baseline	0.784		0.046		0.345		0.206		0.508
Group1 T2-T1	0.28	0.416	-0.43	0.315	0.89	0.073	1.20	0.144	0.44	0.262
T3-T1	-0.44	0.215	-0.76	0.112	-0.91	0.113	-0.82	0.279	-0.79	0.099
Group 0 T2-T1	-0.49	0.605	0.54	0.599	-1.16	0.299	-1.50	0.184	-0.65	0.512
T3-T1	-0.76	0.431	-1.04	0.319	-1.39	0.168	1.42	0.224	-0.93	0.368
HDL/P value at baseline	0.415		0.241		0.790		0.769		0.045
Group1 T2-T1	-0.51	0.439	0.59	0.520	-0.50	0.572	-1.90	0.106	-0.58	0.441
T3-T1	-1.13	0.100	0.61	0.560	0.37	0.740	-1.49	0.270	0.24	0.797
Group 0 T2-T1	1.21	0.548	-2.05	0.369	0.82	0.702	1.10	0.631	3.15	0.135
Continue:	Total resistance		despair		Difficulty		Therapy		Emotions
T3-T1	1.14	0.570	-2.51	0.283	0.57	0.749	0.76	0.739	2.27	0.296
	Total resistance		despair		Difficulty		Therapy		Emotions
LDL/P value at baseline	0.699		0.235		0.322		0.975		0.267
Group1 T2-T1	-2.58	0.451	-5.35	0.210	-4.34	0.557	-7.47	0.144	-4.25	0.271
T3-T1	-0.50	0.889	1.43	0.766	2.97	0.557	2.26	0.672	-0.15	0.973
Group 0 T2-T1	-3.66	0.539	-6.75	0.298	5.31	0.356	-1.52	0.818	4.04	0.481
T3-T1	-3.17	0.594	-6.35	0.357	4.37	0.479	-3.54	0.592	2.43	0.703
TG/P value at baseline	0.564		0.740		0.095		0.791		0.535
Group1 T2-T1	-3.63	0.602	-1.90	0.840	-17.79	0.068	2.99	0.777	-1.00	0.901
T3-T1	9.90	0.169	23.53	0.042	6.67	0.541	4.85	0.645	14.16	0.154
Group 0 T2-T1	17.29	0.303	12.42	0.462	37.2	0.049	-5.49	0.733	12.68	0.449
T3-T1	18.50	0.271	15.21	0.390	38.4	0.050	8.23	0.609	26.52	0.135

Group 1: achieved reduction at T2 (delta between T2 and T1 <0); group 0: those who failed to achieve reduction (delta between T2 and T1 = >0).
† Estimate = delta between time points ^αP Value for differences between groups at baseline.
Models for Emotions were adjusted for age; models for difficulty were adjusted for family status; models for despair were adjusted for education and family status.

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ISSN: 1472-6823

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