| Number of patients | |
---|---|---|
Clinical characteristics | UIHC | WCMC |
Decreased production or intake of vitamin D | Â | Â |
  Severe malnutrition | 6 | -b |
  Skin damage (e.g., burns) | 0 | 0 |
Malabsorption of vitamin D or deficient 25-hydroxylation | Â | Â |
  Liver failure and/or biliary tract dysfunction | 26 | 1 |
  Other disorder with lipid malabsorption | 25 | 0 |
Increased loss of 25(OH)D | Â | Â |
  Nephrotic syndrome | 5 | 1 |
  Renal failure | 23 | 2 |
Increased catabolism or 1α-hydroxylation of 25(OH)D |  |  |
  Liver-enzyme inducing medications | 7 | 0 |
  Hyperthyroidism | 0 | 0 |
  Granulomatous disease | 4 | 0 |
Other conditions possibly linked to 25(OH)D deficiency | Â | Â |
  Morbid obesity and/or status post bariatric surgery | 23 | 4 |
  Systemic lupus erythematosus without lupus nephritis | 8 | 0 |
  Systemic lupus erythematosus with lupus nephritis | 4 | 0 |
Unknown/Other | 51 | 3 |
  Perinatally acquired HIV; now in adolescence or adulthood | 0 | 2 |
  Primary hyperparathyroidism | 3 | 0 |