Skip to main content

Advertisement

Table 3 Performance of HOMA-IR values in the classification of cardio metabolic risk (both ATPIII MetS and IDF MetS definition), influence of age and gender

From: Insulin resistance (HOMA-IR) cut-off values and the metabolic syndrome in a general adult population: effect of gender and age: EPIRCE cross-sectional study

   ROC coefficients* P value AUC (95% CI)
A Males    
IDF MetS    
• Age 0.0102 0.1665 0.69 (0.65, 0.74)
• Intercept −1.1411 0.0048  
ATPIII Mets    
• Age 0.0117 0.1897 0.72 (0.67, 0.77)
• Intercept −1.2976 0.0089  
  Females **    
  IDF MetS    
• Age 30 yr    0.82 (0.71, 0.90)
• Age 50 yr   <0.001 0.77 (0.68, 0.82)
• Age 70 yr    0.58 (0.48, 0.68)
  ATPIII MetS    
• Age 30 yr    0.83 (0.71, 0.91)
• Age 50 yr   0.012 0.80 (0.71, 0.85)
• Age 70 yr    0.61 (0.52, 0.70)
B Males    
IDF MetS    
• Age −0.0113 0.8998 0.68 (0.59, 0.78)
• Intercept 0.1406 0.5160  
ATPIII MetS    
• Age −0.0029 0.8595 0.72 (0.62, 0.81)
• Intercept −0.4692 0.6515  
  Females    
  IDF MetS    
• Age −0.0010 0.9656 0.54 (0.44, 0.64)
• Intercept 0.0173 0.9914  
  ATPIII MetS    
• Age −0.0010 0.9656 0.54 (0.44, 0.64)
  • Intercept 0.0173 0.9914  
  1. Areas under the ROC curves for non-diabetic (A) and diabetic (B) adults (n = 2459).
  2. AUC (95% CI), area under the ROC curve (95% Confidence Interval). *ROC regression models incorporating age as covariate. **The AUC was estimated for three ages (30, 50, and 70 years) to illustrate the performance of HOMA-IR. HOMA-IR, homeostasis model assessment of IR; ATPIII, Third Adult Treatment Panel; IDF, International Diabetes Federation; MetS, Metabolic Syndrome.