Skip to main content

Table 2 Nailfold capillaroscopy, laser Doppler flowmetry, retinal vessel and 24-hr ABPM parameters and effect of gender, microvascular complications and average HbA1c

From: Non-invasive detection of microvascular changes in a paediatric and adolescent population with type 1 diabetes: a pilot cross-sectional study

 

Gender

 

Microvascular Complications

Average HbA1c (%)

 

z

Male

Female

p=

Absent

Present

p=

≤8

>8

p=

n

13

13

 

22

4

 

13

13

 

NC*: Avascular areas (number/nailbed)

1.0 (0.5-1.4)

1.1 (0.9-1.2)

0.74

0.9 (0.7-1.1)

1.6 (0.8-2.3)

0.03

0.9 (0.5-1.2)

1.2 (0.8-1.5)

0.22

NC: micro-aneurysms (number/nailbed)

0.5 (0.3-0.6)

0.6 (0.5-0.7)

0.06

0.5 (0.4-0.6)

0.7 (0.0-0.0)

0.20

0.5 (0.4-0.6)

0.6 (0.4-0.7)

0.55

Laser Doppler flowmetry: Baseline perfusion (PU1)

19.1(10.3-3.4)**

19.1 (11.6-26.6)

1.00

20.6 (14.2-27.1)

10.5 (6.8-14.3)

0.19

18.3 (9.3-27.3)

19.9 (12.7-27.1)

0.78

Retinal vessel analysis: Arteriole-to-venule ratio

0.7 (0.7-0.7)

0.7 (0.7-0.7)

0.56

0.7 (0.7-0.7)

0.07 (0.7-0.8)

0.41

0.7 (0.7-0.7)

0.7 (0.7-0.7)

0.96

24-hr ABPM: BP Dip

7.1 (3.56-10.6)

9.2 (6.6-11.8)

0.32

7.8 (5.4-10.2)

10.1 (4.0-16.1)

0.46

7.4 (3.6-11.2)

8.9 (6.7-11.2)

0.48

  1. *NC (Nailfold Capillaroscopy) **Values presented as mean (95% CI) 1Perfusion units.