Behavioral and clinical correlates of serum bilirubin concentrations in Japanese men and women

BMC Endocrine Disorders

Table 3 Multiple linear regression of serum total bilirubin (mg/dL) in natural logarithm on clinical covariates

Covariate	Men		Women
	β (SE)	P	β (SE)	P
Diastolic BP (per 10 mmHg)	0.0061 (0.0049)	0.22	0.0100 (0.0040)	0.01
Non-HDL cholesterol (per 10 mg/dL)	−0.0078 (0.0017)	< 0.0001	0.0018 (0.0014)	0.19
HDL cholesterol (per 10 mg/dL)	0.0165 (0.0040)	< 0.0001	0.0252 (0.0029)	< 0.0001
HbA1c (per 1.0%)	−0.0187 (0.0069)	0.007	−0.0411 (0.0087)	< 0.0001
Use of antihypertensives	−0.0313 (0.0138)	0.02	0.0051 (0.0124)	0.68
Use of cholesterol-lowering drug	−0.0779 (0.0201)	0.0001	0.0258 (0.0128)	0.05
Use of antidiabetics	−0.0070 (0.0256)	0.78	0.0467 (0.0309)	0.13

BP, blood pressoure; HDL, high-density lipoprotein.
Included in the model were age (year), hours of fasting (< 4, 4–7 and ≥ 8 hours), time of blood drawing (< 12, 12–14 and ≥ 14 hours), season (winter/spring and summer/autumn), smoking (never, past and current smokers with < 15, 15–29 and ≥ 30 cigarettes/day), alcohol intake (never, past and current drinkers with a consumption of < 25, 25–49 and ≥ 50 g/day), body mass index (< 22.5, 22.5–24.9, 25.0–27.4 and ≥ 27.5 kg/m ²), job-related and leisure-time physical activities (quartiles), coffee (0, < 1, 1–3, 4–6 and ≥ 7 cups/day), tea (< 1, 1–3, 4–6, 7–9 and ≥ 10 cups/day) and all of the listed variables.

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