From: The long-term coronary heart disease risk of previously obese patients with type 2 diabetes mellitus
 | MAXBMI, kg/m2 | ||||
---|---|---|---|---|---|
Less than 22.0 | 22.0 to less than 25.0 (reference) | 25.0 to less than 27.5 | 27.5 to less than 30 | 30.0 or greater | |
Number of patients (men/women) | 22 (15/7) | 84 (63/21) | 95 (80/15) | 66 (48/18) | 48 (31/17) |
Age (years) | 52.4 ± 5.6 | 53.4 ± 7.5 | 52.8 ± 6.3 | 53.5 ± 6.7 | 53.3 ± 6.2 |
Observation period (years) | 14.5 ± 3.6 | 12.6 ± 5.4 | 12.3 ± 5.9 | 11.9 ± 5.6 | 11.4 ± 5.1 |
Ex/present smokers (%) | 22.7/45.5 | 28.6/27.4 | 30.5/40.0 | 36.3/33.3 | 14.6/39.6 |
MAXBMI (kg/m2) | 21.0 ± 0.86§ | 23.7 ± 0.77 | 26.2 ± 0.65§ | 28.5 ± 0.66§ | 32.6 ± 2.12§ |
DeltaBMI (kg/m2) | 2.17 ± 1.38§ | 3.21 ± 1.68 | 3.47 ± 1.81 | 4.89 ± 2.13§ | 7.63 ± 3.13§ |
Time interval between MAXBMI and BMI at enrollment (years) | 8.5 (4–14.5) | 15 (6–15) | 8.5 (4–15) †| 9 (3.5-16.5)* | 15 (10–22) |
BMI at enrollment (kg/m2) | 18.9 ± 1.7* | 20.5 ± 1.7 | 22.8 ± 1.9§ | 23.6 ± 2.2§ | 25.0 ± 2.7§ |
HbA1c (%) | 9.2 ± 1.8 | 9.2 ± 2.0 | 9.0 ± 2.1 | 9.8 ± 2.0 | 9.9 ± 2.1 |
Medications for hyperglycemia | Â | ||||
OHA (%) | 45.5 | 40.5 | 49.5 | 42.4 | 47.9 |
Insulin (%) | 22.7 | 11.9 | 8.4 | 12.1 | 14.6 |
Total cholesterol (mmol/L) | 5.54 ± 0.86 | 5.37 ± 1.33 | 5.23 ± 0.99 | 5.60 ± 1.14 | 5.60 ± 1.18 |
HDL cholesterol (mmol/L) | 1.47 ± 0.45* | 1.20 ± 0.34 | 1.14 ± 0.30 | 1.11 ± 0.26 | 1.10 ± 0.28 |
LDL cholesterol (mmol/L) | 3.52 ± 0.88 | 3.49 ± 1.28 | 3.24 ± 0.92 | 3.64 ± 1.03 | 3.57 ± 0.97 |
Triglyceride (mmol/L) | 1.34 ± 0.66 | 1.81 ± 1.78 | 2.06 ± 1.54 | 2.07 ± 1.40 | 2.24 ± 1.59 |
Systolic blood pressure (mmHg) | 130.9 ± 18.5 | 128.0 ± 20.1 | 128.9 ± 17.4 | 131.2 ± 17.9 | 132.6 ± 18.5 |
Diastolic blood pressure (mmHg) | 77.0 ± 10.1 | 75.7 ± 12.1 | 79.3 ± 10.7 | 80.2 ± 9.7 | 78.7 ± 12.6 |
Medications for hypertension (%) | 0.0 | 6.0 | 17.9 | 12.1 | 8.3 |
Diabetic retinopathy (%) | 22.7 | 27.7 | 20.0 | 36.4 | 50.0§ |