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Figure 3 | BMC Endocrine Disorders

Figure 3

From: Evaluating hormonal mechanisms of vitamin D receptor agonist therapy in diabetic kidney disease: the VALIDATE-D study

Figure 3

Reciprocal relationship between renal-vascular tissue-RAS activity and the renal-vascular response to angiotensin II. A blunted response to angiotensin II reflects a high level of local, endogenous, renal-vascular tissue-RAS activity (the smaller the decline in renal plasma flow in response to an infusion of angiotensin II, the greater the activity of the local renal-vascular tissue-RAS). Conversely, a robust response to angiotensin II is observed when tissue-RAS activity is low.

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