All | No adrenal insufficiency | Adrenal insufficiency | P value | |
---|---|---|---|---|
Number of patients | 281 | 249 | 32 | |
Women | 132 (47.0) | 113 (45.4) | 19 (59.4) | 0.19 |
Age (mean) | 67 ± 16 | 68 ± 16 | 63 ± 15 | 0.10 |
Symptoms | ||||
Abdominal pain | 35 (12.5) | 30 (12.1) | 5 (15.6) | 0.57 |
Hypotension symptoms | 12 (4.3) | 12 (4.8) | 0 (0.0) | 0.37 |
Fatigue | 48 (17.1) | 40 (16.1) | 8 (25.0) | 0.31 |
Glucocorticoid withdrawal | 53 (18.9) | 36 (14.5) | 17 (53.1) | <0.001 |
Nausea | 21 (7.5) | 16 (6.4) | 5 (15.6) | 0.07 |
Generalized weakness | 40 (14.2) | 33 (13.3) | 7 (21.9) | 0.19 |
Signs | ||||
Eosinophilia | 2 (0.7) | 1 (0.4) | 1 (3.1) | 0.22 |
Low blood pressure | 141 (50.2) | 125 (50.2) | 16 (50.0) | 0.87 |
Vitiligo | 2 (0.7) | 1 (0.4) | 1 (3.1) | 0.22 |
Biological markers | ||||
Acidosis | 7 (2.5) | 7 (2.8) | 0 (0.0) | 1.00 |
Hypercalcaemia | 10 (3.6) | 10 (4.0) | 0 (0.0) | 0.61 |
Hyperkaliemia | 35 (12.5) | 28 (11.2) | 7 (21.9) | 0.09 |
Hyponatremia | 87 (31.0) | 80 (32.1) | 7 (21.9) | 0.31 |