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Table 1 Clinical characteristics of the patients with adrenal insufficiency, versus control group

From: Predictive factors of adrenal insufficiency in patients admitted to acute medical wards: a case control study

  All No adrenal insufficiency Adrenal insufficiency P value
Number of patients 281 249 32  
Women 132 (47.0) 113 (45.4) 19 (59.4) 0.19
Age (mean) 67 ± 16 68 ± 16 63 ± 15 0.10
Symptoms     
 Abdominal pain 35 (12.5) 30 (12.1) 5 (15.6) 0.57
 Hypotension symptoms 12 (4.3) 12 (4.8) 0 (0.0) 0.37
 Fatigue 48 (17.1) 40 (16.1) 8 (25.0) 0.31
 Glucocorticoid withdrawal 53 (18.9) 36 (14.5) 17 (53.1) <0.001
 Nausea 21 (7.5) 16 (6.4) 5 (15.6) 0.07
 Generalized weakness 40 (14.2) 33 (13.3) 7 (21.9) 0.19
Signs     
 Eosinophilia 2 (0.7) 1 (0.4) 1 (3.1) 0.22
 Low blood pressure 141 (50.2) 125 (50.2) 16 (50.0) 0.87
 Vitiligo 2 (0.7) 1 (0.4) 1 (3.1) 0.22
Biological markers     
 Acidosis 7 (2.5) 7 (2.8) 0 (0.0) 1.00
 Hypercalcaemia 10 (3.6) 10 (4.0) 0 (0.0) 0.61
 Hyperkaliemia 35 (12.5) 28 (11.2) 7 (21.9) 0.09
 Hyponatremia 87 (31.0) 80 (32.1) 7 (21.9) 0.31
  1. Definitions: low blood pressure (<100 mmHg systolic and/or <50 mmHg diastolic blood pressure), vitiligo and/or skin changes. Biological markers collected were: hyperkalemia (>5 mmol/l), hyponatremia (<135 mmol/l), acidosis (pH <7.35), hypercalcaemia (total and ionized, corrected calcium >2.5 mmol/l) and eosinophilia (>0.5 G/l). Results are expressed as number of patients and (percentage). Statistical analysis performed using chi-square or Fischer’s exact test.