Table 1 Allele distributions and HWE P value of the four SNPs in IL21 gene and two SNPs in IL-21R gene
SNP ID | HWE P value | Associated allele | Count (frequency %) | GD P value (OR,95% CI) | HT P value (OR,95% CI) | ||||
|---|---|---|---|---|---|---|---|---|---|
Control | GD | HT | Control | GD | HT | ||||
IL-21 | |||||||||
rs907715 | 0.634 | 0.968 | 0.085 | A | 208(44.6) | 348(44.5) | 210(46.9) | 0.963 | 0.497 |
rs4833837 | 0.999 | 0.300 | 0.715 | G | 56(11.6) | 86(10.6) | 44(9.6) | 0.606 | 0.340 |
rs2221903 | 0.055 | 0.329 | 0.715 | A | 405(84.7) | 721(89.2) | 412(90.4) | 0.018 (1.50, 1.07-2.09) | 0.009 (1.69,1.13-2.51) |
rs2055979 | 0.507 | 0.999 | 0.484 | T | 186(38.9) | 312(39.7) | 160(36.5) | 0.782 | 0.458 |
IL-21R | |||||||||
rs3093301 | 0.427 | 0.732 | 0.172 | T | 228(47.1) | 387(48.0) | 192(42.3) | 0.752 | 0.138 |
rs2285452 | 0.326 | 0.510 | 0.830 | A | 55(11.3) | 89(11.0) | 36(7.9) | 0.797 | 0.068 |