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Table 2 Mean change in A1C (ITT analyses)

From: Real-world utilization patterns and outcomes of colesevelam hcl in the ge electronic medical record

Time point LOCF within day window Target day Actual day N A1C (%)
Mean Baseline mean Post mean Change mean (95% CI)
Week 16 42 - 140 112 97.0 1385 8.22 7.75 −0.47 (−0.53, -0.41)
Week 26 42 - 210 182 146.2 1747 8.25 7.81 −0.44 (−0.50, -0.38)
Week 52 42 - 395 365 297.6 1747 8.25 7.79 −0.46 (−0.52, -0.40)
  1. P < 0.0001 for all based on t-test of change from baseline to last measure within measurement interval; CI: confidence interval.