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Table 5 Comparison between factors and occurrence of drug use problems, drug interactions, and other problems

From: Drug related problems in type 2 diabetes patients with hypertension: a cross-sectional retrospective study

Factors

Drug use problems (n = 50) Frequency (Percentage, %)

Drug interactions (n = 63) Frequency (Percentage, %)

Other problems (n = 97) Frequency (Percentage, %)

 

Yes

No

p -value

Yes

No

p -value

Yes

No

p -value

Elderly

Yes

17 (34.0)

68 (45.3)

0.215a

37 (58.7)

78 (56.9)

0.933a

57 (58.8)

58 (56.3)

0.836a

No

33 (66.0)

82 (54.7)

 

26 (41.3)

59 (43.1)

 

40 (41.2)

45 (43.7)

Polypharmacy

Yes

34 (68.0)

119 (79.3)

0.149a

58 (92.1)

95 (69.3)

0.001a*

74 (76.3)

79 (76.7)

> 0.999a

No

16 (32.0)

31 (20.7)

 

5 (7.9)

42 (30.7)

 

23 (23.7)

24 (23.3)

Duration of hospital stay

≤ 1 week

37 (74.0)

106 (70.7)

0.786a

44 (69.8)

99 (72.3)

0.854a

65 (67.0)

78 (75.7)

0.227a

> 1 week

13 (26.0)

44 (29.3)

 

19 (30.2)

38 (27.7)

 

32 (33.0)

25 (24.3)

Microvascular complications

Yes

31 (62.0)

93 (62.0)

> 0.999a

41 (65.1)

83 (60.6)

0.652a

65 (67.0)

59 (57.3)

0.204a

No

19 (38.0)

57 (38.0)

 

22 (34.9)

54 (39.4)

 

32 (33.0)

44 (42.7)

Cardiovascular disease

Yes

27 (54.0)

94 (62.7)

0.358a

53 (84.1)

68 (49.6)

< 0.001a*

63 (64.9)

58 (56.3)

0.270a

No

23 (46.0)

56 (37.3)

 

10 (15.9)

69 (50.4)

 

34 (35.1)

45 (43.7)

Renal impairment

Yes

22 (44.0)

78 (52.0)

0.414a

33 (52.4)

67 (48.9)

0.761a

49 (50.5)

51 (49.5)

> 0.999a

No

28 (56.0)

72 (48.0)

 

30 (47.6)

70 (51.1)

 

48 (49.5)

52 (50.5)

Liver impairement

Yes

4 (8.0)

7 (4.7)

0.472b

0 (0)

11 (8.0)

0.018b*

5 (5.2)

5 (5.8)

> 0.999a

No

46 (92.0)

143 (95.3)

 

63 (100)

126 (92.0)

 

92 (94.8)

97 (94.2)

Hyperlipidemia

Yes

17 (34.0)

68 (45.3)

 

37 (58.7)

78 (56.9)

 

57 (58.8)

58 (56.3)

0.836a

No

33 (66.0)

82 (54.7)

0.215a

26 (41.3)

59 (43.1)

0.933a

40 (41.2)

45 (43.7)

  1. a Computed using Continuity Correction; b Computed using Fisher’s Exact Test; * Statistically significant (p < 0.05).