Figure 3
An abdominal lymph node biopsy suggests the diagnosis of diffuse large-B cell lymphoma, anaplastic subtype. (A) At low magnification, the normal nodal architecture was totally effaced and the node was diffusely infiltrated by a population of large atypical lymphocytes with a highly characteristic morphology. Extensive infiltration of the perinodal adipose tissue was observed as well. (Haematoxylin and eosin). (B) High magnification show that nuclei were round to oval with fine chromatin; Extensive areas of coagulative necrosis and karyorrhectic nuclei were present. Reed-Sternberg–like forms and giant cells are also prominent and conspicuous nucleoli are seen in these cells. Eosinophilic region was seen near the nucleus, probably representing a prominent Golgi apparatus.