From: Serum prolactin concentrations as risk factor of metabolic syndrome or type 2 diabetes?
Metabolic syndrome | Type 2 diabetes mellitus | |||||||
---|---|---|---|---|---|---|---|---|
Cross-sectional | Longitudinal | Cross-sectional | Longitudinal | |||||
Age-adjusted model | Multivariable model | Age-adjusted model | Multivariable model | Age-adjusted model | Multivariable model | Age-adjusted model | Multivariable model | |
Prolactin | Men | |||||||
per SD increase | 0.95 (0.89; 1.02) | 0.95 (0.89; 1.01) | 1.05 (0.95; 1.15) | 1.04 (0.95; 1.14) | 0.84 (0.73; 0.96)* | 0.83 (0.72; 0.95)* | 1.20 (0.98; 1.47) | 1.19 (0.96; 1.47) |
Quartiles (Q4 Ref.) | ||||||||
Q1 | 1.15 (0.97; 1.37) | 1.15 (0.98; 1.35) | 0.83 (0.64; 1.06) | 0.87 (0.68; 1.10) | 1.55 (1.12; 2.13)* | 1.55 (1.13; 2.14)* | 0.71 (0.41; 1.23) | 0.78 (0.45; 1.35) |
Q2 | 1.06 (0.89; 1.28) | 1.03 (0.87; 1.22) | 0.94 (0.74; 1.19) | 0.94 (0.75; 1.18) | 1.14 (0.81; 1.61) | 1.11 (0.79; 1.56) | 0.73 (0.42; 1.26) | 0.78 (0.45; 1.33) |
Q3 | 1.04 (0.87; 1.25) | 1.02 (0.85; 1.21) | 0.91 (0.72; 1.16) | 0.94 (0.75; 1.18) | 0.92 (0.63; 1.33) | 0.92 (0.64; 1.33) | 0.76 (0.44; 1.32) | 0.72 (0.41; 1.27) |
P for Trend | 0.104 | 0.076 | 0.172 | 0.276 | 0.002 | 0.002 | 0.253 | 0.472 |
Women | ||||||||
per SD increase | 0.92 (0.85; 1.00) | 0.97 (0.90; 1.05) | 0.89 (0.79; 1.00) | 0.92 (0.83; 1.02) | 0.81 (0.68; 0.95)* | 0.84 (0.71; 0.98)* | 1.09 (0.82; 1.45) | 1.13 (0.89; 1.44) |
Quartiles (Q4 Ref.) | ||||||||
Q1 | 1.32 (1.04; 1.66)* | 1.11 (0.89; 1.39) | 1.26 (0.95; 1.68) | 1.15 (0.86; 1.53) | 1.89 (1.21; 2.96)* | 1.70 (1.10; 2.62)* | 0.88 (0.44; 1.78) | 0.73 (0.37; 1.43) |
Q2 | 1.13 (0.89; 1.44) | 1.04 (0.83; 1.32) | 1.22 (0.91; 1.63) | 1.16 (0.87; 1.54) | 1.82 (1.15; 2.86)* | 1.69 (1.09; 2.63)* | 0.81 (0.39; 1.68) | 0.75 (0.37; 1.50) |
Q3 | 1.11 (0.86; 1.44) | 1.07 (0.83; 1.32) | 0.73 (0.51; 1.04) | 0.78 (0.55; 1.11) | 1.29 (0.77; 2.16) | 1.26 (0.76; 2.09) | 1.00 (0.48; 2.06) | 1.08 (0.53; 2.20) |
P for Trend | 0.016 | 0.399 | 0.013 | 0.106 | 0.001 | 0.007 | 0.633 | 0.224 |