Variables | Obese PCOS | p-value | Non-Obese PCOS | p-value | ||
---|---|---|---|---|---|---|
Baseline | 6 months | Baseline | 6 months | |||
BMI (kg/m2) | 32.56 ± 1.13 | 29.71 ± 0.94 | 0.001† | 22.26 ± 0.55 | 21.72 ± 0.66 | 0.263 |
WHR | 0.87 ± 0.01 | 0.86 ± 0.01 | 0.440 | 0.77 ± 0.01 | 0.75 ± 0.01 | 0.056 |
Glucose (mg/dl) | 88.40 ± 1.62 | 84.60 ± 3.96 | 0.117 | 80.80 ± 1.91 | 80.80 ± 2.18 | 0.859 |
HOMA-IR | 4.48 ± 0.42 | 3.29 ± 0.30 | 0.002† | 2.46 ± 0.17 | 2.10 ± 0.23 | 0.139 |
QUICKI | 0.31 ± 0.004 | 0.32 ± 0.005 | 0.003† | 0.33 ± 0.003 | 0.34 ± 0.005 | 0.074 |
Insulin (μU/ml) | 20.48 ± 1.79 | 15.85 ± 1.49 | 0.002† | 12.43 ± 0.85 | 10.57 ± 1.11 | 0.169 |
TC (mg/dl) | 202 ± 20.65 | 220 ± 37.84 | 0.057 | 192 ± 29.24 | 208.20 ±20.77 | 0.047* |
TG (mg/dl) | 103.20 ± 35.41 | 135 ± 72.67 | 0.004† | 96.60 ± 33.48 | 111 ± 49.69 | 1.00 |
Total fat mass (%) | 49.51 ± 3.30 | 47.43 ± 4.36 | 0.016* | 35.94 ± 4.37 | 35.26 ± 3.71 | 0.508 |
Trunk fat mass (%) | 51.82 ± 3.56 | 50.39 ± 4.00 | 0.173 | 35.86 ± 5.44 | 34.46 ± 5.00 | 0.203 |
Lean mass (kg) | 40.54 ± 8.52 | 38.72 ± 8.27 | 0.006† | 36.75 ± 2.38 | 36.51 ± 2.56 | 0.721 |
TT (ng/ml) | 0.86 ± 0.08 | 0.68 ± 0.03 | 0.009† | 0.80 ± 0.09 | 0.68 ± 0.01 | 0.241 |
FAI (%) | 12.33 ± 2.64 | 4.56 ± 1.64 | 0.011* | 5.74 ± 0.82 | 2.04 ± 0.41 | 0.007† |
F-G score | 10.40 ± 1.42 | 8.67 ±1.21 | 0.007† | 8.70 ± 1.64 | 7.50 ± 1.45 | 0.016* |
SHBG (nmol/l) | 35.98 ± 6.10 | 144.03 ± 23.03 | 0.001† | 57.05 ± 8.59 | 155.06 ± 22.53 | 0.013* |
SBP (mmHg) | 109.67 ± 3.02 | 104.67 ±3.29 | 0.042* | 101.00 ± 3.63 | 103.00 ± 3.59 | 0.732 |
DBP (mmHg) | 74.67 ± 2.41 | 74.67 ± 1.91 | 0.886 | 65.00 ± 2.35 | 69.50 ± 2.93 | 0.098 |
HsCRP (mg/l) | 6.10 ± 0.91 | 6.88 ± 1.14 | 0.307 | 3.40 ± 1.03 | 2.69 ± 0.95 | 0.646 |
FMD (%) | 4.57 ± 1.31 | 8.58 ± 1.29 | 0.133 | 1.65 ± 1.44 | 5.55 ± 1.65 | 0.161 |
Baseline artery diameter (mm) | 3.15 ± 0.11 | 3.06 ± 0.09 | 0.402 | 3.12 ± 0.08 | 2.99 ± 0.09 | 0.779 |
ET-1 (pg/ml) | 2.36 ± 0.92 | 1.80 ± 0.42 | 0.198 | 1.71 ± 0.55 | 1.32 ± 0.20 | 0.508 |