Table 1 PCOS subjects (n=25) characteristics at baseline and at the sixth cycles of treatment. Data as means ± SEM

BMI (kg/m²)

28.44 ± 1.24

26.51 ± 1.00

<0.001^‡

WHR

0.83 ± 0.07

0.82 ± 0.01

0.071

Glucose (mg/dl)

85.36 ± 1.43

83.08 ± 1.29

0.192

HOMA-IR

3.67 ± 0.32

2.82 ± 0.23

<0.001^‡

QUICKI

0.31 ± 0.003

0.33 ± 0.004

0.001^†

Insulin (μU/ml)

17.26 ± 1.37

13.74 ± 1.11

0.001^†

TC (mg/dl)

198.00±4.87

215.28 ± 6.42

0.005^†

TG (mg/dl)

100.56 ± 6.82

125.40 ± 12.88

0.04*

Total fat mass (%)

44.08 ± 1.54

42.56 ± 1.47

0.018*

Trunk fat mass (%)

45.44 ± 1.81

44.02 ± 1.81

0.065

Lean mass (kg)

39.03 ± 1.38

37.84 ± 1.32

0.009^†

TT (ng/ml)

0.84 ± 0.06

0.68 ± 0.02

0.007^†

FAI (%)

9.70 ± 1.72

3.55 ±1.02

<0.001^‡

SHBG (nmol/l)

44.41 ± 5.34

148.44 ± 16.22

<0.001^‡

F-G score

9.72 ± 1.06

8.20 ± 0.92

0.02*

SBP (mmHg)

106.20 ± 2.43

104.00 ±2.39

0.184

DBP (mmHg)

70.80 ± 1.95

72.60 ± 1.68

0.318

hsCRP (mg/l)

5.02 ± 0.72

5.20 ± 0.87

0.518

FMD (%)

3.48 ± 1.00

7.43 ± 1.04

0.033*

Baseline artery diameter (mm)

3.14 ± 0.07

3.03 ± 0.06

0.039*

ET-1 (pg/ml)

2.10 ± 0.59

1.60 ± 0.26

0.179