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Table 3 Predictors of change in biochemical parameters during four weeks of vitamin D3 supplementation (n = 55)

From: Changes in the vitamin D endocrine system and bone turnover after oral vitamin D3 supplementation in healthy adults: results of a randomised trial

Dependent variable

Δs-25(OH)D (nmol/l)

Δs-iPTH (pmol/l)

Δs-1,25(OH)2D (pmol/l)

Δs-TRACP (U/L)

B

(95% CI)

p value

B

(95% CI)

p value

B

(95% CI)

p value

B

(95% CI)

p value

Type of supplement (solid multivitamin tablet vs. gelatine fish oil capsule with n-3 fatty acids) (1)

3.5 (2) (−3.6, 10.6)

0.33

−0.4 (−1.5, 0.6)

0.39

−1 (−22, 19)

0.89

−0.08 (−0.25, 0.10)

0.40

Age, per 10 years

1.4 (−3.2, 6.0)

0.54

−0.5 (−1.3, 0.4)

0.31

−10 (−27, 7)

0.24

0.07 (−0.05, 0.19)

0.25

Gender, men vs. women

1.0 (−6.4, 8.5)

0.78

−1.3 (−2.5, 0.3)

0.11

18 (−8, 46)

0.17

0.04 (−0.16, 0.23)

0.71

Body mass index, per 5 kg/m2

−1.0 (−5.7, 3.7)

0.68

−0.3 (−1.2, 0.6)

0.48

−9 (−26, 8)

0.30

0.05 (−0.07, 0.17)

0.41

Ethnic background, Tamil vs. Norwegian

2.7 (−6.0, 11.3)

0.54

−0.5 (−2.2, 1.2)

0.54

−18 (−51, −14)

0.26

0.27 (0.05, 0.49)

0.016

Baseline s-25(OH)D, per 10 nmol/l

−1.1 (−2.6, 0.4)

0.13

0.2 (−0.1, 0.5)

0.10

−3 (−8, 3)

0.31

−0.03 (−0.07, 0.01)

0.10

Baseline s-iPTH, per 5 pmol/l

4.4 (−2.3, 11.2)

0.20

−3.2 (−4.2, −2.3)

< 0.001

−13 (−38, 12)

0.30

−0.04 (−0.22, 0.14)

0.66

Baseline s-1,25(OH)2D, per 10 pmol/l

−0.3 (−1.2, 0.6)

0.51

0.0 (−0.2, 0.1)

0.71

−8 (−10, −5)

< 0.001

< −0.01 (−0.03, 0.02)

0.81

Baseline s-TRACP, per U/l

−4.7 (−9.8, 0.3)

0.07

0.1 (−0.9, 1.1)

0.86

9 (−10, 28)

0.34

−0.13 (−0.26, -0.01)

0.039

  1. 1 Groups are randomised with regard to type of supplement. The analysis of type of supplement is adjusted for baseline serum concentration of the respective dependent variables, while the other analyses in the table are unadjusted.
  2. 2 Result previously published in: Holvik K et al., Br J Nutr 2007; 98: 620–5.