Skip to main content

Table 2 Mixed meal test results (median (IQ range)) by 90 minute MMT stimulated C-peptide (SCP, nmol/L) tertile

From: Assessment of endogenous insulin secretion in insulin treated diabetes predicts postprandial glucose and treatment response to prandial insulin

 

Tertile 1 (SCP ≤ 0.02,n = 27)

Tertile 2 (SCP 0.02-0.8, n = 27)

Tertile 3 (SCP ≥ 0.8, n = 26)

p for trend

Glucose increment in MMT (without insulin, mmol/L)

10.6 (9.0-13.7)

9.9 (8.2-11.0)

7.1 (4.4-8.9)

0.001

Glucose increment in MMT+I (insulin given, mmol/L)

4.3 (0.4-8.8)

4.4 (2.2-4.4)

5.2 (3.6-6.4)

0.45

Reduction in glucose increment when prandial insulin given (mmol/L): all participants (n = 80)

6.4 (4.2-11.1)

4.0 (2.5-7.9)

1.2 (0.03-2.88)

0.001

Reduction in glucose increment when prandial insulin given (mmol/L): Rapid analogue insulin only* (n = 61):

6.7 (4.3-11.2)

4.0 (2.3-7.9)

1.4 (1.8-3.0)

0.001

Reduction in glucose increment when prandial insulin given (mmol/L): Type 1 only (n = 54)

6.9 (4.2-11.3)

4.0 (2.4-7.8)

1.9 (0.3-3.5)

0.002

Reduction in glucose increment when prandial insulin given (mmol/L): Type 2 only (n = 26):

5.1 (4.2-6)

4.5 (2.4-9.2),

1.1 (−0.3-2.4)

0.006

  1. Participants completing both MMT and MMTI only.
  2. *excluding premixed insulin.