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Table 1 Characteristics of participants (median (IQ range)) by 90 minute MMT stimulated C-peptide (SCP, nmol/L) tertile

From: Assessment of endogenous insulin secretion in insulin treated diabetes predicts postprandial glucose and treatment response to prandial insulin

 

Tertile 1 (SCP ≤ 0.02,n = 27)

Tertile 2 (SCP 0.02-0.8, n = 27)

Tertile 3 (SCP ≥ 0.8, n = 26)

p for trend

Age (years)

53 (42–62)

42 (30–64)

62 (37–71)

0.70

Age of diagnosis (years)

15 (8–23)

27 (21–44)

50 (28–59)

0.001

Duration of Diabetes

36 (26–45)

16 (3–21)

10 (2–15)

0.001

BMI

26 (23–28)

25 (23–29)

29 (25–37)

0.013

HbA1c (%)

7.9 (7.2-8.7)

7.7 (7.0-8.7)

7.9 (7.4-8.7)

0.57

HbA1c (mmol/mol)

63 (55–72)

60 (53–71)

63 (57–72)

0.57

Proportion Type 1 diabetes

93%

78%

31%

0.001

Fasting glucose (mmol/L) (Test 1)

10.1(7.9-12.9)

8.8 (6.4-12.8)

8.4 (7.0-10.5)

0.064

90 Minute post MMT C-peptide (nmol/L)

0.01 (0–0.01)

0.40 (0.23-0.65)

1.79 (1.12-2.30)

0.001

Prandial (rapid or soluble only*) insulin dose administered in MMT+I (units)

8 (5–10)

8 (6–12)

6.3 (4.8-12.3)

0.98

Total daily insulin dose (units)

46 (33–64)

42 (28–62)

45 (26–88)

0.90

  1. Participants completing both MMT and MMTI only.
  2. * where participant took a mixed morning insulin the rapid/soluble component was calculated.