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Table 2 Adjusted geometric means of HbA1c for quartiles of gamma-glutamyltransferase (GGT) by bilirubin and coffee consumption*

From: No effect modification of serum bilirubin or coffee consumption on the association of gamma-glutamyltransferase with glycated hemoglobin in a cross-sectional study of Japanese men and women

  

GGT†

   

Trend

Interaction

Stratification

n

Q1 (lowest)

Q2

Q3

Q4 (highest)

P

P

Men

       

Bilirubin (mg/dL)

       

 Low (< 0.6)

2313

5.02 (4.97–5.07)

5.11 (5.06–5.16)

5.21 (5.16–5.26)

5.26 (5.20–5.31)

< 10–9

0.72

 High (≥ 0.6)

2179

4.95 (4.89–5.00)

5.02 (4.97–5.07)

5.12 (5.07–5.17)

5.20 (5.15–5.25)

< 10–10

 

Coffee (cups/day)

       

 < 1

1911

5.00 (4.95–5.06)

5.07 (5.02–5.13)

5.14 (5.09–5.20)

5.24 (5.18–5.29)

< 10–6

0.64

 1–3

2036

4.96 (4.91–5.01)

5.05 (5.00–5.10)

5.16 (5.11–5.21)

5.20 (5.14–5.26)

< 10–9

 

 ≥ 4

545

5.03 (4.94–5.12)

5.13 (5.03–5.23)

5.27 (5.17–5.37)

5.32 (5.19–5.45)

< 10–3

 

Women

       

Bilirubin (mg/dL)

       

 Low (< 0.5)

2910

5.02 (4.99–5.05)

5.10 (5.07–5.13)

5.18 (5.15–5.21)

5.19 (5.16–5.22)

< 10–16

0.22

 High (≥ 0.5)

3332

4.99 (4.96–5.02)

5.03 (5.01–5.06)

5.07 (5.04–5.10)

5.14 (5.11–5.17)

< 10–12

 

Coffee (cups/day)

       

 < 1

2623

5.02 (4.99–5.06)

5.06 (5.03–5.10)

5.12 (5.09–5.15)

5.17 (5.14–5.20)

< 10–9

0.86

 1–3

3081

4.99 (4.96–5.02)

5.07 (5.05–5.10)

5.13 (5.10–5.16)

5.15 (5.12–5.18)

< 10–15

 

 ≥ 4

538

4.99 (4.93–5.06)

5.02 (4.95–5.09)

5.08 (5.01–5.15)

5.17 (5.09–5.24)

< 10–3

 
  1. In parentheses are 95% confidence intervals of geometric means.
  2. * Adjusted for age, smoking, alcohol intake and body mass index by analysis of covariance.
  3. † The first to the fourth quartile (Q1 to Q4) categories were ≤ 23, 24–35, 36–58 and ≥ 59 IU/L in men; and ≤ 15, 16–20, 21–29 and ≥ 30 IU/L in women.
  4. ‡ Ordinal values were assigned to GGT categories.