Table 1 Patient characteristics, risk factors, laboratory values
Incident hypo 12 months FU Median (quartiles) or % (n=473) | No hypo 12 months FU Median (quartiles) or % (n=2874) | p-value / OR (95%CI) | |
|---|---|---|---|
Age (years) | 66.8 (57.8-74.1) | 65.9 (57.6-72.7) | 0.08 |
Female gender (%) | 43.8 | 47.5 | 0.14 |
Diabetes duration (years) | 6.4 (3.0-10.5) | 5.5 (2.9-9.2) | <0.01 |
Blood glucose | |||
HbA1c (%) | 7.6 (6.8-8.8) | 7.4 (6.8-8.1) | <0.0001 |
HbA1c ≥ 7.5% | 55.9 | 46.2 | <0.001 |
FPG (mg/dl) | 142 (115–174) | 140 (119–168) | 0.83 |
PPG (mg/dl) | 183 (156–222) | 183 (155–220) | 0.39 |
Blood glucose self measurement (%) | 87.7 | 73.9 | <0.0001 |
Prior smoker (%) | 20.9 | 14.2 | <0.001 |
Bodyweight (kg) | 87 (78–98) | 89 (78–100) | 0.09 |
Coronary artery disease (%) | 22.0 | 17.5 | <0.05 |
Stroke / TIA (%) | 5.7 | 4.5 | 0.23 |
PAD (%) | 8.6 | 5.7 | <0.05 |
Amputation (%) | 2.3 | 0.7 | <0.001 |
Heart failure (%) | 13.1 | 9.3 | <0.05 |
Autonomous neuropathy (%) | 4.2 | 3.4 | 0.41 |
Peripheral neuropathy (%) | 17.6 | 12.9 | <0.01 |
NPDR (%) | 7.4 | 3.2 | <0.0001 |
PDR (%) | 1.7 | 0.3 | <0.0001 |
Clinically relevant depression (%) | 8.4 | 4.8 | <0.01 |