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Table 1 Description of study population and anti-hypertensive treatment of the groups

From: Unilateral adrenal hyperplasia is a usual cause of primary hyperaldosteronism. Results from a Swedish screening study

 

Population

The rest of the screening population

SPA-group

 

All (n = 307)

SP (n = 94)

NSP (n = 213)

All (n =46)

SP (n = 28)

NSP (n = 18)

Female

164

47

117

18

11

7

Male

189

75

114

28

7

21

Age (years)

60.0 ± 11.1

56.0 ± 11.9

61.8 ± 10.3

59.7 ± 10.6

56.3 ± 10.8

65.1 ± 7.9

BMI (kg/m 2 )

28.7 ± 4.5

28.4 ± 5.2

28.8 ± 4.2

29.0 ± 4.2

28.6 ± 3.8

29.6 ± 4.7

Mean SBP (mmHg)

146.9 ± 21.0

149.9 ± 22.3

145.6 ± 20.4

152.0 ± 20.9

152.2 ± 20.9

152.7 ± 21.5

Mean DBP(mmHg

86.8 ± 10.6

87.5 ± 10.5

86.4 ± 10.7

91.0 ± 9.0

91.0 ± 8.1

90.9 ± 10.5

Duration of HT (years)

12.6 ± 9.8

13.1 ± 9.3

12.3 ± 10.1

12.9 ± 6.9

12.9 ± 5.6

12.8 ± 8.8

No of drugs*

1.8 ± 1.1

2.3 ± 1.3

1.6 ± 0.9

2.4 ± 1.1

2.6 ± 1.3

2.1 ± 0.8

No of drugs 0 to 3

279

75

204

39

21

18

No of drugs 4 to 5

26

18

8

7

7

0

β-blockers

165

60

105

34

22

12

ACE – & AII-inhibitors

154

60

94

24

16

8

diuretics

131

47

84

18

13

5

Spironolactone

0

0

0

2

2

0

Potassium supplements

14

8

6

3

3

0

Serum Potassium (mmol/l)

4.0 ± 0.4

3.9 ± 0.4

4.0 ± 0.4

3.7 ± 0.3

3.7 ± 0.5

3.7 ± 0.3

  1. The rest of the screening population (n = 307 = 353-46, i.e. the whole screening population – the SPA group) and the group suspected with primary hyperaldosteronism (the SPA group) due to the defined cut-off limits for serum aldosterone and serum aldosterone/renin ratio (ARR). SP = selected population. NSP = non-selected population. No of medicine = total number of antihypertensive drugs at the time of screening, presented as the mean value ± standard deviation. Respective antihypertensive drug is presented as total number of patients treated with it. β-blockers = β –receptor inhibitor. ACE = angiotensin converting enzyme. AII = angiotensin II. *Information on drugs is missing for 2 patients not being in the SPA-group.