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Table 1 Clinical characteristics of subjects

From: Serum levels of pancreatic stone protein (PSP)/reg1A as an indicator of beta-cell apoptosis suggest an increased apoptosis rate in hepatocyte nuclear factor 1 alpha (HNF1A-MODY) carriers from the third decade of life onward

Subject group

HNF1A-MODY

Glucokinase Mutations

Type 1 diabetes mellitus

Number of subjects

37

13

27

Age (yrs)

43 (21–52)

38 (27–60)

41 (23–52)

Diabetes duration (yrs)

6 (3–19)

From birth

21 (3–34)

BMI (kg/m 2 )

24.4 (22.0-26.3)

24.0 (21.6-26.4)

24.4 (22.3-28.6)

Fasting plasma glucose (mmol/l)

6.8 (5.4-9.0)

6.5 (6.0-7.0)

9.6 (8.5-11.1)

Fasting C peptide (ng/ml)

1.5 (1.0-1.8)

1.3 (1.0-1.7)

<0.5a

HbA 1c (%)

7.0 (6.3-7.9)

6.3 (6.1-6.6)

7.7 (7.2-9.2)

  1. Clinical characteristics of subjects with HNF1A-MODY, GCK-MODY, type 1 diabetes mellitus,
  2. a = median is below detection limit. Data are given as median (IQR).