Parameters | NGT | Pre-diabetes | p value |
---|---|---|---|
(n = 24) | (n = 26) | ||
Anthropometric measures | |||
Age (years) | 36 ± 2 | 39 ± 2 | 0.232 |
Weight (Kg) | 69 ± 2 | 77 ± 3* | 0.026 |
Body Mass Index (kg/m2) | 24.0 ± 0.6 | 26.5 ± 0.6* | 0.005 |
Waist Circumference (cm) | 90.3 ± 1.7 | 98.3 ± 3.1* | 0.032 |
Waist - Hip Ratio | 0.96 ± 0.01 | 0.98 ± 0.01 | 0.070 |
Systolic Blood Pressure (mmHg) | 119.0 ± 1.8 | 122.8 ± 2.6 | 0.240 |
Diastolic Blood Pressure (mmHg) | 76.3 ± 1.6 | 76.6 ± 1.9 | 0.992 |
Biochemical parameters | |||
OGTT | |||
Fasting plasma glucose (mmol/l) | 5.0 ± 0.1 | 5.7 ± 0.1** | 0.0001 |
2Hr Post plasma glucose (mmol/l) | 5.6 ± 0.2 | 8.1 ± 0.3** | 0.0001 |
Glycated Hemoglobin [HbA1c] (%) | 5.4 ± 0.1 | 5.8 ± 0.1* | 0.0013 |
Fasting Insulin (pmol/l) | 49.8 ± 5 | 95.1 ± 10** | 0.0002 |
2Hr post Insulin (pmol/l) | 325.8 ± 49 | 780.0 ± 75** | 0.0001 |
HOMA-IR | 1.9 ± 0.2 | 4.0 ± 0.4** | 0.0001 |
Lipid profile | |||
Total Cholesterol (mmol/l) | 4.6 ± 0.2 | 4.9 ± 0.2 | 0.376 |
Serum Triglycerides (mmol/l) | 1.51 ± 0.2 | 1.9 ± 0.2 | 0.166 |
HDL Cholesterol (mmol/l) | 1.0 ± 0.04 | 0.9 ± 0.04 | 0.459 |
LDL Cholesterol (mmol/l) | 2.9 ± 0.1 | 3.0 ± 0.2 | 0.632 |
VLDL Cholesterol (mmol/l) | 0.7 ± 0.1 | 0.9 ± 0.1 | 0.163 |
Others | |||
Serum Creatinine (μmol/l) | 79.6 ± 1.8 | 106.9 ± 27.1 | 0.364 |
Hs-CRP (mg/l) | 2.5 ± 0.5 | 3.1 ± 0.5 | 0.341 |
Microalbuminuria (μg/mg) | 5.2 ± 0.8 | 7.6 ± 1.5 | 0.344 |