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Table 5 12-month changes from baseline in MetS components and cardiovascular values by baseline testosterone level quartiles

From: Effect of 12 months of testosterone replacement therapy on metabolic syndrome components in hypogonadal men: data from the Testim Registry in the US (TRiUS)

 

Quartile 1

(<206 ng/dL)

[<7.1 nmol/L]

Quartile 2

(206-256 ng/dL)

[7.1-8.9 nmol/L]

Quartile 3

(257-330 ng/dL)

[8.9-11.5 nmol/L]

Quartile 4

(≥331 ng/dL)

[≥11.5 nmol/L]

Differences Among Quartiles

 

Mean Change from Baseline

(p-Value)

p-Value

Waist circumference,

cm [inches]

-2.1 [-0.84]

(0.002)

-1.2 [-0.49]

(0.1)

+0.5 [+0.20]

(0.5)

-0.1 [-0.03]

(0.9)

0.06

FBG,

mg/dL [mmol/L]

-11.5 [-0.64]

(0.01)

+0.76 [+0.04]

(0.9)

-7.7 [-0.43]

(0.1)

+1.1 [+0.06]

(0.8)

0.2

Systolic BP,

mmHg

-1.5

(0.4)

-1.0

(0.6)

-2.9

(0.2)

+1.9

(0.4)

0.4

Diastolic BP, mmHg

-1.5

(0.2)

-2.3

(0.07)

-2.5

(0.09)

+0.3

(0.8)

0.4

HDL cholesterol, mg/dL [mmol/L]

-0.45 [-0.01]

(0.8)

-2.1 [-0.05]

(0.3)

-0.89 [-0.02]

(0.6)

+0.54 [+0.01]

(0.8)

0.8

Plasma TG, mg/dL [mmol/L]

-17.8 [-0.20]

(0.3)

-11.4 [-0.12]

(0.6)

-34.2 [-0.39]

(0.08)

+2.1 [+0.02]

(0.9)

0.7

  1. BP = blood pressure; FBG = fasting blood glucose; HDL = high-density lipoprotein; MetS = metabolic syndrome; TG = triglycerides.