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Table 3 Odds ratios for metabolic or glycemic abnormality associated with elevated biomarkers of inflammation and endothelial dysfunction

From: Association of inflammation and endothelial dysfunction with metabolic syndrome, prediabetes and diabetes in adults from Inner Mongolia, China

 

No Prediabetes,

Diabetes, or MetS

Prediabetes or

Diabetes only

MetS without

Prediabetes or

Diabetes

MetS plus

Prediabetes or

Diabetes

hsCRP (mg/L)

Age, gender

1.00

2.27 (1.69, 3.06)

3.00 (2.35, 3.84)

5.84 (4.53, 7.53)

Multivariable

1.00

2.22 (1.65, 3.00)

2.97 (2.33, 3.80)

5.70 (4.41, 7.33)

Multivariable + BMI

1.00

2.29 (1.69, 3.10)

2.38 (1.82, 3.11)

4.82 (3.69, 6.31)

sICAM-1 (ng/ml)

Age, gender

1.00

2.14 (1.60, 2.86)

1.13 (0.88, 1.46)

4.15 (3.24, 5.31)

Multivariable

1.00

2.06 (1.54, 2.76)

1.10 (0.85, 1.43)

3.98 (3.10, 5.12)

Multivariable + BMI

1.00

2.11 (1.58, 2.83)

0.91 (0.69, 1.21)

3.43 (2.64, 4.47)

sE-selectin (ng/mL)

Age, gender

1.00

0.82 (0.60, 1.12)

1.71 (1.35, 2.17)

1.27 (0.99, 1.62)

Multivariable

1.00

0.82 (0.60, 1.13)

1.71 (1.35, 2.17)

1.28 (1.00, 1.64)

Multivariable + BMI

1.00

0.85 (0.62, 1.17)

1.38 (1.06, 1.79)

1.06 (0.81, 1.38)

Angiotensin II (pg/mL)

Age, gender

1.00

0.63 (0.45, 0.87)

1.09 (0.85, 1.39)

1.05 (0.82, 1.35)

Multivariable

1.00

0.63 (0.45, 0.87)

1.06 (0.83, 1.36)

1.00 (0.78, 1.29)

Multivariable + BMI

1.00

0.62 (0.45, 0.86)

1.12 (0.86, 1.46)

1.05 (0.80, 1.37)

  1. Abbreviations: MetS, Metabolic Syndrome; hsCRP, high sensitivity C-reactive protein; sICAM-1, soluble Intercellular adhesion molecule-1; sE-selectin, soluble E-selectin; BG, blood glucose. The multivariable models are adjusted for age, gender, smoking, drinking and family history of hypertension.