Table 2 Markers of bone turnover and BMD in patients with Graves' disease and toxic multinodular goiter versus control.
Parameters | GD (n = 31) | TNG (n = 21) | Controls (n = 25) | Significant | ||
|---|---|---|---|---|---|---|
P1 | P2 | P3 | ||||
Serum B-ALP (KAU/l) | 4.9 ± 3.6 | 4.3 ± 2.6 | 2.2 ± 0.8 | <0.01 | <0.01 | >0.05 |
Serum calcium (mg/dl) | 9.5 ± 1.0 | 9.8 ± 1.0 | 9.8 ± 0.5 | >0.05 | >0.05 | >0.05 |
Serum phosphorus (mg/dl) | 3.9 ± 0.6 | 4.0 ± 0.6 | 4.0 ± 0.7 | >0.05 | >0.05 | >0.05 |
Serum osteocalcin (ng/ml) | 12.9 ± 4.0 | 11.9 ± 4.1 | 6.6 ± 1.6 | <0.0001 | <0.0001 | >0.05 |
Serum β-CTx (ug/l) | 4.5 ± 0.8 | 4.1 ± 0.6 | 3.3 ± 0.6 | <0.01 | <0.01 | >0.05 |
Ur. calcium/urinary creatinine | 0.54 ± 0.07 | 0.49 ± 0.05 | 0.36 ± 0.05 | <0.001 | <0.01 | >0.05 |
UDXP (nmol/l) | 68 ± 24 | 73 ± 22 | 49.8 ± 26 | <0.01 | <0.01 | >0.05 |
UDXP/urinary creatinine | 12.6 ± 5.5 | 13.5 ± 5.0 | 6.3 ± 1.8 | <0.001 | <0.001 | >0.05 |
BMD at lower radius (g/cm 2 ) | 0.780 ± 0.215 | 0.799 ± 0.232 | 0.952 ± 0.170 | <0.01 | <0.01 | >0.05 |