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Table 2 Markers of bone turnover and BMD in patients with Graves' disease and toxic multinodular goiter versus control.

From: Impact of severity, duration, and etiology of hyperthyroidism on bone turnover markers and bone mineral density in men

Parameters GD
(n = 31)
TNG
(n = 21)
Controls
(n = 25)
Significant
     P1 P2 P3
Serum B-ALP (KAU/l) 4.9 ± 3.6 4.3 ± 2.6 2.2 ± 0.8 <0.01 <0.01 >0.05
Serum calcium (mg/dl) 9.5 ± 1.0 9.8 ± 1.0 9.8 ± 0.5 >0.05 >0.05 >0.05
Serum phosphorus (mg/dl) 3.9 ± 0.6 4.0 ± 0.6 4.0 ± 0.7 >0.05 >0.05 >0.05
Serum osteocalcin (ng/ml) 12.9 ± 4.0 11.9 ± 4.1 6.6 ± 1.6 <0.0001 <0.0001 >0.05
Serum β-CTx (ug/l) 4.5 ± 0.8 4.1 ± 0.6 3.3 ± 0.6 <0.01 <0.01 >0.05
Ur. calcium/urinary creatinine 0.54 ± 0.07 0.49 ± 0.05 0.36 ± 0.05 <0.001 <0.01 >0.05
UDXP (nmol/l) 68 ± 24 73 ± 22 49.8 ± 26 <0.01 <0.01 >0.05
UDXP/urinary creatinine 12.6 ± 5.5 13.5 ± 5.0 6.3 ± 1.8 <0.001 <0.001 >0.05
BMD at lower radius (g/cm 2 ) 0.780 ± 0.215 0.799 ± 0.232 0.952 ± 0.170 <0.01 <0.01 >0.05
  1. Data: Mean ± SD
  2. Significant P at < 0.05