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  1. Research article

    Urinary iodine in early pregnancy is associated with subclinical hypothyroidism in Tianjin, China: an observational study

    Subclinical hypothyroidism (SH) is associated with adverse obstetric outcomes and neurodevelopment disorders. Both iodine deficiency and excess are associated with SH; however, few data regarding iodine nutrit...

    Kunling Wang, Jie Zhang, Fengao Li, Wanqi Zhang, Hao Wang, Li Ding, Yaxin Liu, Laixiang Lin, Shuang Zhang and Mei Zhu

    BMC Endocrine Disorders 2017 17:10

    Published on: 17 February 2017

  2. Case report

    Corticomedullary mixed tumour resembling a small adrenal gland-involvement of cancer stem cells: case report

    Adrenal corticomedullary mixed tumours are very rare. Its mechanism is rarely reported. Here we report the first case of a corticomedullary mixed tumour resembling a “small adrenal gland” with distinct arrange...

    Lian Duan, Fang Fang, Wanlei Fu, Zhenqiang Fang, Hui Wang, Shicang Yu, Zili Tang, Zhenqi Liu and Hongting Zheng

    BMC Endocrine Disorders 2017 17:9

    Published on: 13 February 2017

  3. Research article

    High-sensitive C-reactive protein and risk of incident type 2 diabetes: a case–control study nested within the Singapore Chinese Health Study

    The liver-derived C-reactive protein (CRP) is a sensitive and systemic biomarker of inflammation, and has been associated with increased risk of developing type 2 diabetes in populations other than Chinese. Th...

    An Pan, Yeli Wang, Jian-Min Yuan and Woon-Puay Koh

    BMC Endocrine Disorders 2017 17:8

    Published on: 8 February 2017

  4. Research article

    Quality of sleep and risk for obstructive sleep apnoea in ambulant individuals with type 2 diabetes mellitus at a tertiary referral hospital in Kenya: a cross-sectional, comparative study

    Sleep disorders are common and associated with multiple metabolic and psychological derangements. Obstructive sleep apnoea (OSA) is among the most common sleep disorders and an inter-relationship between OSA, ...

    Sairabanu Mohammed Rashid Sokwalla, Mark David Joshi, Erastus Olonde Amayo, Kirtida Acharya, Jared Ongechi Mecha and Kenneth Kipyegon Mutai

    BMC Endocrine Disorders 2017 17:7

    Published on: 6 February 2017

  5. Study protocol

    Study protocol; Thyroid hormone Replacement for Untreated older adults with Subclinical hypothyroidism - a randomised placebo controlled Trial (TRUST)

    Subclinical hypothyroidism (SCH) is a common condition in elderly people, defined as elevated serum thyroid-stimulating hormone (TSH) with normal circulating free thyroxine (fT4). Evidence is lacking about the...

    David J. Stott, Jacobijn Gussekloo, Patricia M. Kearney, Nicolas Rodondi, Rudi G. J. Westendorp, Simon Mooijaart, Sharon Kean, Terence J. Quinn, Naveed Sattar, Kirsty Hendry, Robert Du Puy, Wendy P. J. Den Elzen, Rosalinde K. E. Poortvliet, Jan W. A. Smit, J. Wouter Jukema, Olaf M. Dekkers…

    BMC Endocrine Disorders 2017 17:6

    Published on: 3 February 2017

  6. Research article

    Short-term effectiveness of low dose liraglutide in combination with metformin versus high dose liraglutide alone in treatment of obese PCOS: randomized trial

    Liraglutide 3 mg was recently approved as an anti-obesity drug. Metformin is weight neutral, yet it could enhance the therapeutic index of GLP-1 agonist. We compared weight-lowering potential of liraglutide 1....

    Mojca Jensterle, Nika Aleksandra Kravos, Katja Goričar and Andrej Janez

    BMC Endocrine Disorders 2017 17:5

    Published on: 31 January 2017

  7. Study protocol

    Self-monitoring of Blood Glucose in Non-Insulin Treated Type 2 Diabetes (The SMBG Study): study protocol for a randomised controlled trial

    The benefit of Self-monitoring of Blood Glucose (SMBG) in people with non-insulin treated type 2 diabetes remains unclear with inconsistent evidence from randomised controlled trials fuelling the continued deb...

    Sharon Parsons, Stephen Luzio, Stephen Bain, John Harvey, Jillian McKenna, Atir Khan, Sam Rice, Alan Watkins and David R. Owens

    BMC Endocrine Disorders 2017 17:4

    Published on: 26 January 2017

  8. Research article

    Prevalence of undiagnosed type 2 diabetes in patients admitted with acute coronary syndrome: the utility of easily reproducible screening methods

    Despite the recognition of the importance of diagnosing dysglycaemia in patients with acute coronary syndrome (ACS) there remains a lack of consensus on the best screening modality. Our primary aims were to de...

    Muhammad A. Karamat, Umar Y. Raja, Susan E. Manley, Alan Jones, Wasim Hanif and Abd A. Tahrani

    BMC Endocrine Disorders 2017 17:3

    Published on: 23 January 2017

  9. Research article

    Frequency and determinants of thyroid autoimmunity in Ghanaian type 2 diabetes patients: a case-control study

    The link between type 1 diabetes and thyroid autoimmunity is well described. The same cannot be said for type 2 diabetes where results have been mixed so far. We investigated the prevalence and determinants of...

    Osei Sarfo-Kantanka, Fred Stephen Sarfo, Eunice Oparebea Ansah, Ernest Yorke, Josephine Akpalu, Bernard C. Nkum and Benjamin Eghan

    BMC Endocrine Disorders 2017 17:2

    Published on: 17 January 2017

  10. Research article

    Genistein treatment improves fracture resistance in obese diabetic mice

    Obese, type two diabetics are at an increased risk for fracturing their limb bones in comparison to the general population. Phytoestrogens like as the soy isoflavone genistein have been shown to protect agains...

    Britton Odle, Nathan Dennison, Layla Al-Nakkash, Tom L. Broderick and Jeffrey H. Plochocki

    BMC Endocrine Disorders 2017 17:1

    Published on: 9 January 2017

  11. Research article

    Effect of sitagliptin on blood glucose control in patients with type 2 diabetes mellitus who are treatment naive or poorly responsive to existing antidiabetic drugs: the JAMP study

    To investigate the ameliorating effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on blood glucose control in patients with type 2 diabetes mellitus who were previously untreated with or who have a po...

    Hiroshi Sakura, Naotake Hashimoto, Kazuo Sasamoto, Hiroshi Ohashi, Sumiko Hasumi, Noriko Ujihara, Tadasu Kasahara, Osamu Tomonaga, Hideo Nunome, Masashi Honda and Yasuhiko Iwamoto

    BMC Endocrine Disorders 2016 16:70

    Published on: 1 December 2016

  12. Research article

    The predictive value of sonographic images of follicular lesions – a comparison with nodules unequivocal in FNA – single centre prospective study

    To determine the diagnostic efficacy of ultrasonographic malignancy risk features (UMRFs) in follicular lesions (FL) in a population with low risk of malignancy in FL and to compare it with a similar analysis ...

    Dorota Słowińska-Klencka, Martyna Wojtaszek-Nowicka, Stanisław Sporny, Ewa Woźniak-Oseła, Bożena Popowicz and Mariusz Klencki

    BMC Endocrine Disorders 2016 16:69

    Published on: 1 December 2016

  13. Research article

    Prevalence and factors associated with diabetes mellitus and impaired fasting glucose level among members of federal police commission residing in Addis Ababa, Ethiopia

    The prevalence of diabetes mellitus and factors associated with it, nowadays, are increasing in alarming rates among different occupational groups. Of these occupational groups are Police officers that, often,...

    Tariku Tesfaye, Bilal Shikur, Tariku Shimels and Naod Firdu

    BMC Endocrine Disorders 2016 16:68

    Published on: 28 November 2016

  14. Research article

    A randomised, open-labelstudy of insulin glargine or neutral protamine Hagedorn insulin in Chinese paediatric patients with type 1 diabetes mellitus

    We aimed to describe the safety and efficacy of insulin glargine in Chinese paediatric patients with type 1 diabetes mellitus (T1DM). Neutral protamine Hagedorn (NPH) insulin was the reference therapy.

    Min Liu, Zhiguang Zhou, Jinhua Yan, Pin Li, Wenhui Song, Junfen Fu, Xiaobo Chen, Weigang Zhao, Li Xi, Xiaoping Luo, Liang Sha, Xueyuan Deng and Chunxiu Gong

    BMC Endocrine Disorders 2016 16:67

    Published on: 26 November 2016

  15. Case report

    Administration of anti-receptor activator of nuclear factor-kappa B ligand (RANKL) antibody for the treatment of osteoporosis was associated with amelioration of hepatitis in a female patient with growth hormone deficiency: a case report

    Growth hormone deficiency (GHD) is associated with non-alcoholic fatty liver disease (NAFLD). A recent animal study showed that hepatocyte-specific receptor activator of nuclear factor-kappa B (RANK) knockout ...

    Ayumu Takeno, Masahiro Yamamoto, Masakazu Notsu and Toshitsugu Sugimoto

    BMC Endocrine Disorders 2016 16:66

    Published on: 24 November 2016

  16. Research article

    Diabetes screening intervals based on risk stratification

    Guidelines for frequency of Type 2 diabetes mellitus (DM) screening remain unclear, with proposed screening intervals typically based on expert opinion. This study aims to demonstrate that HbA1c screening inte...

    Sachiko Ohde, Emily McFadden, Gautam A. Deshpande, Hiroshi Yokomichi, Osamu Takahashi, Tsuguya Fukui, Rafael Perera and Zentaro Yamagata

    BMC Endocrine Disorders 2016 16:65

    Published on: 22 November 2016

  17. Research article

    Acute glycaemic effects of co-trimoxazole at prophylactic dose in healthy adults

    Cases of severe hypoglycaemia were reported in HIV/AIDS patients receiving high dose of the sulfonylurea co-trimoxazole for opportunistic infections. Whether co-trimoxazole at prophylactic dose would induce si...

    Bernold Kenteu, Jean Jacques N. Noubiap, Martine Claude Etoa, Marcel Azabji-Kenfack, Mesmin Dehayem and Eugene Sobngwi

    BMC Endocrine Disorders 2016 16:62

    Published on: 15 November 2016

  18. Research article

    The course of diabetes in children, adolescents and young adults: does the autoimmunity status matter?

    Initial classification of diabetes of young may require revision to improve diagnostic accuracy of different forms of diabetes.

    Rasa Verkauskiene, Evalda Danyte, Rimante Dobrovolskiene, Ingrida Stankute, Diana Simoniene, Dovile Razanskaite-Virbickiene, Audrone Seibokaite, Brone Urbonaite, Nijole Jurgeviciene, Astra Vitkauskiene, Valerie Schwitzgebel and Dalia Marciulionyte

    BMC Endocrine Disorders 2016 16:61

    Published on: 15 November 2016

  19. Research article

    Obesity and diabetes mellitus association in rural community of Katana, South Kivu, in Eastern Democratic Republic of Congo: Bukavu Observ Cohort Study Results

    Factual data exploring the relationship between obesity and diabetes mellitus prevalence from rural areas of sub-Saharan Africa remain scattered and are unreliable. To address this scarceness, this work report...

    Philippe Bianga Katchunga, Justin Cikomola, Christian Tshongo, Arsene Baleke, David Kaishusha, Patrick Mirindi, Théodore Tamburhe, Yves Kluyskens, Antoine Sadiki, Socrate Bwanamudogo, Zacharie Kashongwe and Marc Twagirumukiza

    BMC Endocrine Disorders 2016 16:60

    Published on: 11 November 2016

  20. Research article

    Gastric bypass surgery reveals independency of obesity and diabetes melitus type 2

    Roux-en-Y gastric bypass surgery is widely applied to ameliorate morbid obesity, including diabetes in people with type 2 diabetes. The latter vanish a few days after surgery for many, but not in all patients ...

    Mogens Fenger, Dorte Lindqvist Hansen, Dorte Worm, Lisbeth Hvolris, Viggo B. Kristiansen, Elin Rebecka Carlsson and Sten Madsbad

    BMC Endocrine Disorders 2016 16:59

    Published on: 9 November 2016

  21. Case report

    Case report of whole genome sequencing in the XY female: identification of a novel SRY mutation and revision of a misdiagnosis of androgen insensitivity syndrome

    The 46,XY female is characterised by a male karyotype and female phenotype arising due to any interruption in the sexual development pathways in utero. The cause is usually genetic and various genes are implicate...

    Sunita M. C. De Sousa, Karin S. Kassahn, Liam C. McIntyre, Chan-Eng Chong, Hamish S. Scott and David J. Torpy

    BMC Endocrine Disorders 2016 16:58

    Published on: 8 November 2016

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