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  1. Case report

    Administration of anti-receptor activator of nuclear factor-kappa B ligand (RANKL) antibody for the treatment of osteoporosis was associated with amelioration of hepatitis in a female patient with growth hormone deficiency: a case report

    Growth hormone deficiency (GHD) is associated with non-alcoholic fatty liver disease (NAFLD). A recent animal study showed that hepatocyte-specific receptor activator of nuclear factor-kappa B (RANK) knockout ...

    Ayumu Takeno, Masahiro Yamamoto, Masakazu Notsu and Toshitsugu Sugimoto

    BMC Endocrine Disorders 2016 16:66

    Published on: 24 November 2016

  2. Research article

    Diabetes screening intervals based on risk stratification

    Guidelines for frequency of Type 2 diabetes mellitus (DM) screening remain unclear, with proposed screening intervals typically based on expert opinion. This study aims to demonstrate that HbA1c screening inte...

    Sachiko Ohde, Emily McFadden, Gautam A. Deshpande, Hiroshi Yokomichi, Osamu Takahashi, Tsuguya Fukui, Rafael Perera and Zentaro Yamagata

    BMC Endocrine Disorders 2016 16:65

    Published on: 22 November 2016

  3. Research article

    Acute glycaemic effects of co-trimoxazole at prophylactic dose in healthy adults

    Cases of severe hypoglycaemia were reported in HIV/AIDS patients receiving high dose of the sulfonylurea co-trimoxazole for opportunistic infections. Whether co-trimoxazole at prophylactic dose would induce si...

    Bernold Kenteu, Jean Jacques N. Noubiap, Martine Claude Etoa, Marcel Azabji-Kenfack, Mesmin Dehayem and Eugene Sobngwi

    BMC Endocrine Disorders 2016 16:62

    Published on: 15 November 2016

  4. Research article

    The course of diabetes in children, adolescents and young adults: does the autoimmunity status matter?

    Initial classification of diabetes of young may require revision to improve diagnostic accuracy of different forms of diabetes.

    Rasa Verkauskiene, Evalda Danyte, Rimante Dobrovolskiene, Ingrida Stankute, Diana Simoniene, Dovile Razanskaite-Virbickiene, Audrone Seibokaite, Brone Urbonaite, Nijole Jurgeviciene, Astra Vitkauskiene, Valerie Schwitzgebel and Dalia Marciulionyte

    BMC Endocrine Disorders 2016 16:61

    Published on: 15 November 2016

  5. Research article

    Obesity and diabetes mellitus association in rural community of Katana, South Kivu, in Eastern Democratic Republic of Congo: Bukavu Observ Cohort Study Results

    Factual data exploring the relationship between obesity and diabetes mellitus prevalence from rural areas of sub-Saharan Africa remain scattered and are unreliable. To address this scarceness, this work report...

    Philippe Bianga Katchunga, Justin Cikomola, Christian Tshongo, Arsene Baleke, David Kaishusha, Patrick Mirindi, Théodore Tamburhe, Yves Kluyskens, Antoine Sadiki, Socrate Bwanamudogo, Zacharie Kashongwe and Marc Twagirumukiza

    BMC Endocrine Disorders 2016 16:60

    Published on: 11 November 2016

  6. Research article

    Gastric bypass surgery reveals independency of obesity and diabetes melitus type 2

    Roux-en-Y gastric bypass surgery is widely applied to ameliorate morbid obesity, including diabetes in people with type 2 diabetes. The latter vanish a few days after surgery for many, but not in all patients ...

    Mogens Fenger, Dorte Lindqvist Hansen, Dorte Worm, Lisbeth Hvolris, Viggo B. Kristiansen, Elin Rebecka Carlsson and Sten Madsbad

    BMC Endocrine Disorders 2016 16:59

    Published on: 9 November 2016

  7. Case report

    Case report of whole genome sequencing in the XY female: identification of a novel SRY mutation and revision of a misdiagnosis of androgen insensitivity syndrome

    The 46,XY female is characterised by a male karyotype and female phenotype arising due to any interruption in the sexual development pathways in utero. The cause is usually genetic and various genes are implicate...

    Sunita M. C. De Sousa, Karin S. Kassahn, Liam C. McIntyre, Chan-Eng Chong, Hamish S. Scott and David J. Torpy

    BMC Endocrine Disorders 2016 16:58

    Published on: 8 November 2016

  8. Research article

    Using Hashimoto thyroiditis as gold standard to determine the upper limit value of thyroid stimulating hormone in a Chinese cohort

    Subclinical hypothyroidism, commonly caused by Hashimoto thyroiditis (HT), is a risk factor for cardiovascular diseases. This disorder is defined as merely having elevated serum thyroid stimulating hormone (TS...

    Yu Li, Dong-Ning Chen, Jing Cui, Zhong Xin, Guang-Ran Yang, Ming-Jia Niu and Jin-Kui Yang

    BMC Endocrine Disorders 2016 16:57

    Published on: 6 November 2016

  9. Research article

    The effect of lifestyle intervention in obesity on the soluble form of activated leukocyte cell adhesion molecule

    The aim of this study was to investigate the effect of a lifestyle intervention in obesity on the soluble form of the activated leukocyte cell adhesion molecule (sALCAM) and its association with metabolic para...

    Alba Sulaj, Johanna Zemva, Ulrike Zech, Annika Woehning, Maik Brune, Gottfried Rudofsky, Peter P. Nawroth, Thomas Fleming and Rüdiger von Bauer

    BMC Endocrine Disorders 2016 16:56

    Published on: 13 October 2016

  10. Research article

    Single-dose acarbose decreased glucose-dependent insulinotropic peptide and glucagon levels in Chinese patients with newly diagnosed type 2 diabetes mellitus after a mixed meal

    Acarbose slows down the intestinal absorption of carbohydrates, but its effects on the secretion of incretins are still poorly known. This study aimed to examine the effects of single-dose acarbose on the secr...

    Zhong Chen, Xiaoying Fu, Jian Kuang, Ju Chen, Hongmei Chen, Jianhao Pei and Huazhang Yang

    BMC Endocrine Disorders 2016 16:55

    Published on: 29 September 2016

  11. Research article

    Gender-modulated risk of coronary heart disease, diabetes and coronary mortality among Turks for three major risk factors, and residual adiposity risk

    We determined the proportion of the effects of body mass index (BMI) or its categories on cardiometabolic outcomes mediated through systolic blood pressure (SBP), total cholesterol and fasting glucose.

    Günay Can, Altan Onat, Eray Yurtseven, Yusuf Karadeniz, Tuğba Akbaş-Şimşek, Ayşem Kaya and Hüsniye Yüksel

    BMC Endocrine Disorders 2016 16:54

    Published on: 29 September 2016

  12. Research article

    Arterial stiffness in hypertensive and type 2 diabetes patients in Ghana: comparison of the cardio-ankle vascular index and central aortic techniques

    Diabetes and hypertension increase arterial stiffness and cardiovascular events in all societies studied so far; sub-Saharan African studies are sparse. We investigated factors affecting arterial function in G...

    Kwame Yeboah, Daniel A. Antwi, Ben Gyan, Virginia Govoni, Charlotte E. Mills, J. Kennedy Cruickshank and Albert G. B. Amoah

    BMC Endocrine Disorders 2016 16:53

    Published on: 29 September 2016

  13. Research article

    Neonatal and obstetric outcomes in diet- and insulin-treated women with gestational diabetes mellitus: a retrospective study

    To evaluate the neonatal and obstetric outcomes of pregnancies complicated by gestational diabetes mellitus (GDM). Screening and treatment – diet-only versus additional insulin therapy – were based on the 2010...

    Sarah H. Koning, Klaas Hoogenberg, Kirsten A. Scheuneman, Mick G. Baas, Fleurisca J. Korteweg, Krystyna M. Sollie, Bertine J. Schering, Aren J. van Loon, Bruce H.R. Wolffenbuttel, Paul P. van den Berg and Helen L. Lutgers

    BMC Endocrine Disorders 2016 16:52

    Published on: 29 September 2016

  14. Research article

    Plantar pressures are higher in cases with diabetic foot ulcers compared to controls despite a longer stance phase duration

    Current international guidelines advocate achieving at least a 30 % reduction in maximum plantar pressure to reduce the risk of foot ulcers in people with diabetes. However, whether plantar pressures differ in...

    Malindu E. Fernando, Robert G. Crowther, Peter A. Lazzarini, Kunwarjit S. Sangla, Scott Wearing, Petra Buttner and Jonathan Golledge

    BMC Endocrine Disorders 2016 16:51

    Published on: 15 September 2016

  15. Research article

    Familial early puberty: presentation and inheritance pattern in 139 families

    The mechanism that initiates the onset of puberty is largely unknown but the age of onset is mainly under genetic control and influenced by environmental factors including nutrition. The coexistence in the sam...

    Adélaïde Durand, Anu Bashamboo, Ken McElreavey and Raja Brauner

    BMC Endocrine Disorders 2016 16:50

    Published on: 13 September 2016

  16. Research article

    Increased skin autofluorescence of children and adolescents with type 1 diabetes despite a well-controlled HbA1c: results from a cohort study

    Early identification of children and adolescents with type 1 diabetes at high risk for development of complications is important, as early intervention may prevent further deterioration. Here we investigate th...

    Josine C. van der Heyden, Erwin Birnie, Dick Mul, Sarah Bovenberg, Henk J. Veeze and Henk-Jan Aanstoot

    BMC Endocrine Disorders 2016 16:49

    Published on: 9 September 2016

  17. Research article

    Adrenal fatigue does not exist: a systematic review

    The term “adrenal fatigue” (“AF”) has been used by some doctors, healthcare providers, and the general media to describe an alleged condition caused by chronic exposure to stressful situations. Despite this, “...

    Flavio A. Cadegiani and Claudio E. Kater

    BMC Endocrine Disorders 2016 16:48

    Published on: 24 August 2016

    The Erratum to this article has been published in BMC Endocrine Disorders 2016 16:63

  18. Research article

    Prevalence of impaired glucose tolerance and other types of dysglycaemia among young twins and singletons in Guinea-Bissau

    Twins may be at increased risk of dysglycaemic disorders due to adverse fetal conditions. Data from Africa regarding this association is limited. We studied impaired glucose tolerance (IGT) and other types of ...

    Ditte Egegaard Hennild, Morten Bjerregaard-Andersen, Luis Carlos Joaquím, Kaare Christensen, Morten Sodemann, Henning Beck-Nielsen and Dorte Møller Jensen

    BMC Endocrine Disorders 2016 16:46

    Published on: 4 August 2016

  19. Research article

    Utility of repeat cytological assessment of thyroid nodules initially classified as benign: clinical insights from multidisciplinary care in an Irish tertiary referral centre

    Fine needle aspiration biopsy (FNAB) is the tool of choice for evaluating thyroid nodules with the majority classified as benign following initial assessment. However, concern remains about false negative resu...

    Nigel Glynn, Mark J. Hannon, Sarah Lewis, Patrick Hillery, Mohammed Al-Mousa, Arnold D. K. Hill, Frank Keeling, Martina Morrin, Christopher J. Thompson, Diarmuid Smith, Derval Royston, Mary Leader and Amar Agha

    BMC Endocrine Disorders 2016 16:45

    Published on: 2 August 2016

  20. Research article

    Elevated circulating irisin is associated with lower risk of insulin resistance: association and path analyses of obese Chinese adults

    Evidence on the role of irisin in insulin resistance is limited and controversial, and pathways between them remain unknown. We aimed to examine the independent effects of circulating irisin and different adip...

    Xiulin Shi, Mingzhu Lin, Changqin Liu, Fangsen Xiao, Yongwen Liu, Peiying Huang, Xin Zeng, Bing Yan, Suhuan Liu, Xiaoying Li, Shuyu Yang, Xuejun Li and Zhibin Li

    BMC Endocrine Disorders 2016 16:44

    Published on: 29 July 2016

  21. Research article

    Development and validation of a Diabetes Risk Score for screening undiagnosed diabetes in Sri Lanka (SLDRISK)

    Screening for undiagnosed diabetes is not widely undertaken due to the high costs and invasiveness of blood sampling. Simple non-invasive tools to identify high risk individuals can facilitate screening. The m...

    P. Katulanda, N. R. Hill, I. Stratton, R. Sheriff, S. D. N. De Silva and D. R. Matthews

    BMC Endocrine Disorders 2016 16:42

    Published on: 25 July 2016

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