Diabetes and Metabolism

Section edited by Abd Tahrani

This section concerns all aspects of diabetes and metabolic syndrome including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. Research article

    Pulse wave velocity and cardiac autonomic function in type 2 diabetes mellitus

    Increased carotid-femoral pulse wave velocity (PWV) has been associated with incident cardiovascular disease, independently of traditional risk factors. Cardiac autonomic dysfunction is a common complication o...

    Stamatina Chorepsima, Ioanna Eleftheriadou, Anastasios Tentolouris, Ioannis Moyssakis, Athanasios Protogerou, Alexandros Kokkinos, Petros P. Sfikakis and Nikolaos Tentolouris

    BMC Endocrine Disorders 2017 17:27

    Published on: 19 May 2017

  2. Study protocol

    Does left ventricular hypertrophy affect cognition and brain structural integrity in type 2 diabetes? Study design and rationale of the Diabetes and Dementia (D2) study

    Cognitive impairment is common in type 2 diabetes mellitus, and there is a strong association between type 2 diabetes and Alzheimer’s disease. However, we do not know which type 2 diabetes patients will dement...

    Sheila K. Patel, Carolina Restrepo, Emilio Werden, Leonid Churilov, Elif I. Ekinci, Piyush M. Srivastava, Jay Ramchand, Bryan Wai, Brian Chambers, Christopher J. O’Callaghan, David Darby, Vladimir Hachinski, Toby Cumming, Geoff Donnan, Louise M. Burrell and Amy Brodtmann

    BMC Endocrine Disorders 2017 17:24

    Published on: 7 April 2017

  3. Research article

    Assessment of platelets morphological changes and serum butyrylcholinesterase activity in children with diabetic ketoacidosis: a case control study

    Many studies indicated that mean platelet volume (MPV) and platelet distribution width (PDW) may be valuable in the diagnosis and management of clinical disorders; also, serum butyrylcholinesterase activity (B...

    Suzan Omar Mousa, Samira Zein Sayed, Mahmoud Mohammed Moussa and Ahmed Hamdy Hassan

    BMC Endocrine Disorders 2017 17:23

    Published on: 4 April 2017

  4. Study protocol

    The effectiveness of a value-based EMOtion-cognition-Focused educatIonal programme to reduce diabetes-related distress in Malay adults with Type 2 diabetes (VEMOFIT): study protocol for a cluster randomised controlled trial

    Type 2 diabetes mellitus (T2DM) patients experience many psychosocial problems related to their diabetes. These often lead to emotional disorders such as distress, stress, anxiety and depression, resulting in ...

    Boon-How Chew, Rimke C. Vos, Sazlina Shariff Ghazali, Nurainul Hana Shamsuddin, Aaron Fernandez, Firdaus Mukhtar, Mastura Ismail, Azainorsuzila Mohd Ahad, Narayanan N. Sundram, Siti Zubaidah Mohd Ali and Guy E. H. M. Rutten

    BMC Endocrine Disorders 2017 17:22

    Published on: 4 April 2017

  5. Case report

    Extended clinical features associated with novel Glis3 mutation: a case report

    Mutations in the GLI-similar 3 (GLIS3) gene encoding the transcription factor GLIS3 are a rare cause of neonatal diabetes and congenital hypothyroidism with 12 reported patients to date. Additional features, p...

    K. A. Alghamdi, A. B. Alsaedi, A. Aljasser, A. Altawil and Naglaa M. Kamal

    BMC Endocrine Disorders 2017 17:14

    Published on: 2 March 2017

  6. Research article

    High-sensitive C-reactive protein and risk of incident type 2 diabetes: a case–control study nested within the Singapore Chinese Health Study

    The liver-derived C-reactive protein (CRP) is a sensitive and systemic biomarker of inflammation, and has been associated with increased risk of developing type 2 diabetes in populations other than Chinese. Th...

    An Pan, Yeli Wang, Jian-Min Yuan and Woon-Puay Koh

    BMC Endocrine Disorders 2017 17:8

    Published on: 8 February 2017

  7. Study protocol

    Self-monitoring of Blood Glucose in Non-Insulin Treated Type 2 Diabetes (The SMBG Study): study protocol for a randomised controlled trial

    The benefit of Self-monitoring of Blood Glucose (SMBG) in people with non-insulin treated type 2 diabetes remains unclear with inconsistent evidence from randomised controlled trials fuelling the continued deb...

    Sharon Parsons, Stephen Luzio, Stephen Bain, John Harvey, Jillian McKenna, Atir Khan, Sam Rice, Alan Watkins and David R. Owens

    BMC Endocrine Disorders 2017 17:4

    Published on: 26 January 2017

  8. Research article

    Prevalence of undiagnosed type 2 diabetes in patients admitted with acute coronary syndrome: the utility of easily reproducible screening methods

    Despite the recognition of the importance of diagnosing dysglycaemia in patients with acute coronary syndrome (ACS) there remains a lack of consensus on the best screening modality. Our primary aims were to de...

    Muhammad A. Karamat, Umar Y. Raja, Susan E. Manley, Alan Jones, Wasim Hanif and Abd A. Tahrani

    BMC Endocrine Disorders 2017 17:3

    Published on: 23 January 2017

  9. Research article

    Frequency and determinants of thyroid autoimmunity in Ghanaian type 2 diabetes patients: a case-control study

    The link between type 1 diabetes and thyroid autoimmunity is well described. The same cannot be said for type 2 diabetes where results have been mixed so far. We investigated the prevalence and determinants of...

    Osei Sarfo-Kantanka, Fred Stephen Sarfo, Eunice Oparebea Ansah, Ernest Yorke, Josephine Akpalu, Bernard C. Nkum and Benjamin Eghan

    BMC Endocrine Disorders 2017 17:2

    Published on: 17 January 2017

  10. Research article

    Genistein treatment improves fracture resistance in obese diabetic mice

    Obese, type two diabetics are at an increased risk for fracturing their limb bones in comparison to the general population. Phytoestrogens like as the soy isoflavone genistein have been shown to protect agains...

    Britton Odle, Nathan Dennison, Layla Al-Nakkash, Tom L. Broderick and Jeffrey H. Plochocki

    BMC Endocrine Disorders 2017 17:1

    Published on: 9 January 2017

  11. Research article

    Effect of sitagliptin on blood glucose control in patients with type 2 diabetes mellitus who are treatment naive or poorly responsive to existing antidiabetic drugs: the JAMP study

    To investigate the ameliorating effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on blood glucose control in patients with type 2 diabetes mellitus who were previously untreated with or who have a po...

    Hiroshi Sakura, Naotake Hashimoto, Kazuo Sasamoto, Hiroshi Ohashi, Sumiko Hasumi, Noriko Ujihara, Tadasu Kasahara, Osamu Tomonaga, Hideo Nunome, Masashi Honda and Yasuhiko Iwamoto

    BMC Endocrine Disorders 2016 16:70

    Published on: 1 December 2016

  12. Research article

    Prevalence and factors associated with diabetes mellitus and impaired fasting glucose level among members of federal police commission residing in Addis Ababa, Ethiopia

    The prevalence of diabetes mellitus and factors associated with it, nowadays, are increasing in alarming rates among different occupational groups. Of these occupational groups are Police officers that, often,...

    Tariku Tesfaye, Bilal Shikur, Tariku Shimels and Naod Firdu

    BMC Endocrine Disorders 2016 16:68

    Published on: 28 November 2016

  13. Research article

    A randomised, open-labelstudy of insulin glargine or neutral protamine Hagedorn insulin in Chinese paediatric patients with type 1 diabetes mellitus

    We aimed to describe the safety and efficacy of insulin glargine in Chinese paediatric patients with type 1 diabetes mellitus (T1DM). Neutral protamine Hagedorn (NPH) insulin was the reference therapy.

    Min Liu, Zhiguang Zhou, Jinhua Yan, Pin Li, Wenhui Song, Junfen Fu, Xiaobo Chen, Weigang Zhao, Li Xi, Xiaoping Luo, Liang Sha, Xueyuan Deng and Chunxiu Gong

    BMC Endocrine Disorders 2016 16:67

    Published on: 26 November 2016

  14. Research article

    Diabetes screening intervals based on risk stratification

    Guidelines for frequency of Type 2 diabetes mellitus (DM) screening remain unclear, with proposed screening intervals typically based on expert opinion. This study aims to demonstrate that HbA1c screening inte...

    Sachiko Ohde, Emily McFadden, Gautam A. Deshpande, Hiroshi Yokomichi, Osamu Takahashi, Tsuguya Fukui, Rafael Perera and Zentaro Yamagata

    BMC Endocrine Disorders 2016 16:65

    Published on: 22 November 2016

  15. Research article

    Acute glycaemic effects of co-trimoxazole at prophylactic dose in healthy adults

    Cases of severe hypoglycaemia were reported in HIV/AIDS patients receiving high dose of the sulfonylurea co-trimoxazole for opportunistic infections. Whether co-trimoxazole at prophylactic dose would induce si...

    Bernold Kenteu, Jean Jacques N. Noubiap, Martine Claude Etoa, Marcel Azabji-Kenfack, Mesmin Dehayem and Eugene Sobngwi

    BMC Endocrine Disorders 2016 16:62

    Published on: 15 November 2016

  16. Research article

    The course of diabetes in children, adolescents and young adults: does the autoimmunity status matter?

    Initial classification of diabetes of young may require revision to improve diagnostic accuracy of different forms of diabetes.

    Rasa Verkauskiene, Evalda Danyte, Rimante Dobrovolskiene, Ingrida Stankute, Diana Simoniene, Dovile Razanskaite-Virbickiene, Audrone Seibokaite, Brone Urbonaite, Nijole Jurgeviciene, Astra Vitkauskiene, Valerie Schwitzgebel and Dalia Marciulionyte

    BMC Endocrine Disorders 2016 16:61

    Published on: 15 November 2016

  17. Research article

    Gastric bypass surgery reveals independency of obesity and diabetes melitus type 2

    Roux-en-Y gastric bypass surgery is widely applied to ameliorate morbid obesity, including diabetes in people with type 2 diabetes. The latter vanish a few days after surgery for many, but not in all patients ...

    Mogens Fenger, Dorte Lindqvist Hansen, Dorte Worm, Lisbeth Hvolris, Viggo B. Kristiansen, Elin Rebecka Carlsson and Sten Madsbad

    BMC Endocrine Disorders 2016 16:59

    Published on: 9 November 2016

  18. Research article

    The effect of lifestyle intervention in obesity on the soluble form of activated leukocyte cell adhesion molecule

    The aim of this study was to investigate the effect of a lifestyle intervention in obesity on the soluble form of the activated leukocyte cell adhesion molecule (sALCAM) and its association with metabolic para...

    Alba Sulaj, Johanna Zemva, Ulrike Zech, Annika Woehning, Maik Brune, Gottfried Rudofsky, Peter P. Nawroth, Thomas Fleming and Rüdiger von Bauer

    BMC Endocrine Disorders 2016 16:56

    Published on: 13 October 2016

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