Diabetes and Metabolism

Section edited by Abd Tahrani

This section concerns all aspects of diabetes and metabolic syndrome including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. Research article

    High-sensitive C-reactive protein and risk of incident type 2 diabetes: a case–control study nested within the Singapore Chinese Health Study

    The liver-derived C-reactive protein (CRP) is a sensitive and systemic biomarker of inflammation, and has been associated with increased risk of developing type 2 diabetes in populations other than Chinese. Th...

    An Pan, Yeli Wang, Jian-Min Yuan and Woon-Puay Koh

    BMC Endocrine Disorders 2017 17:8

    Published on: 8 February 2017

  2. Study protocol

    Self-monitoring of Blood Glucose in Non-Insulin Treated Type 2 Diabetes (The SMBG Study): study protocol for a randomised controlled trial

    The benefit of Self-monitoring of Blood Glucose (SMBG) in people with non-insulin treated type 2 diabetes remains unclear with inconsistent evidence from randomised controlled trials fuelling the continued deb...

    Sharon Parsons, Stephen Luzio, Stephen Bain, John Harvey, Jillian McKenna, Atir Khan, Sam Rice, Alan Watkins and David R. Owens

    BMC Endocrine Disorders 2017 17:4

    Published on: 26 January 2017

  3. Research article

    Prevalence of undiagnosed type 2 diabetes in patients admitted with acute coronary syndrome: the utility of easily reproducible screening methods

    Despite the recognition of the importance of diagnosing dysglycaemia in patients with acute coronary syndrome (ACS) there remains a lack of consensus on the best screening modality. Our primary aims were to de...

    Muhammad A. Karamat, Umar Y. Raja, Susan E. Manley, Alan Jones, Wasim Hanif and Abd A. Tahrani

    BMC Endocrine Disorders 2017 17:3

    Published on: 23 January 2017

  4. Research article

    Frequency and determinants of thyroid autoimmunity in Ghanaian type 2 diabetes patients: a case-control study

    The link between type 1 diabetes and thyroid autoimmunity is well described. The same cannot be said for type 2 diabetes where results have been mixed so far. We investigated the prevalence and determinants of...

    Osei Sarfo-Kantanka, Fred Stephen Sarfo, Eunice Oparebea Ansah, Ernest Yorke, Josephine Akpalu, Bernard C. Nkum and Benjamin Eghan

    BMC Endocrine Disorders 2017 17:2

    Published on: 17 January 2017

  5. Research article

    Genistein treatment improves fracture resistance in obese diabetic mice

    Obese, type two diabetics are at an increased risk for fracturing their limb bones in comparison to the general population. Phytoestrogens like as the soy isoflavone genistein have been shown to protect agains...

    Britton Odle, Nathan Dennison, Layla Al-Nakkash, Tom L. Broderick and Jeffrey H. Plochocki

    BMC Endocrine Disorders 2017 17:1

    Published on: 9 January 2017

  6. Research article

    Effect of sitagliptin on blood glucose control in patients with type 2 diabetes mellitus who are treatment naive or poorly responsive to existing antidiabetic drugs: the JAMP study

    To investigate the ameliorating effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on blood glucose control in patients with type 2 diabetes mellitus who were previously untreated with or who have a po...

    Hiroshi Sakura, Naotake Hashimoto, Kazuo Sasamoto, Hiroshi Ohashi, Sumiko Hasumi, Noriko Ujihara, Tadasu Kasahara, Osamu Tomonaga, Hideo Nunome, Masashi Honda and Yasuhiko Iwamoto

    BMC Endocrine Disorders 2016 16:70

    Published on: 1 December 2016

  7. Research article

    Prevalence and factors associated with diabetes mellitus and impaired fasting glucose level among members of federal police commission residing in Addis Ababa, Ethiopia

    The prevalence of diabetes mellitus and factors associated with it, nowadays, are increasing in alarming rates among different occupational groups. Of these occupational groups are Police officers that, often,...

    Tariku Tesfaye, Bilal Shikur, Tariku Shimels and Naod Firdu

    BMC Endocrine Disorders 2016 16:68

    Published on: 28 November 2016

  8. Research article

    A randomised, open-labelstudy of insulin glargine or neutral protamine Hagedorn insulin in Chinese paediatric patients with type 1 diabetes mellitus

    We aimed to describe the safety and efficacy of insulin glargine in Chinese paediatric patients with type 1 diabetes mellitus (T1DM). Neutral protamine Hagedorn (NPH) insulin was the reference therapy.

    Min Liu, Zhiguang Zhou, Jinhua Yan, Pin Li, Wenhui Song, Junfen Fu, Xiaobo Chen, Weigang Zhao, Li Xi, Xiaoping Luo, Liang Sha, Xueyuan Deng and Chunxiu Gong

    BMC Endocrine Disorders 2016 16:67

    Published on: 26 November 2016

  9. Research article

    Diabetes screening intervals based on risk stratification

    Guidelines for frequency of Type 2 diabetes mellitus (DM) screening remain unclear, with proposed screening intervals typically based on expert opinion. This study aims to demonstrate that HbA1c screening inte...

    Sachiko Ohde, Emily McFadden, Gautam A. Deshpande, Hiroshi Yokomichi, Osamu Takahashi, Tsuguya Fukui, Rafael Perera and Zentaro Yamagata

    BMC Endocrine Disorders 2016 16:65

    Published on: 22 November 2016

  10. Research article

    Acute glycaemic effects of co-trimoxazole at prophylactic dose in healthy adults

    Cases of severe hypoglycaemia were reported in HIV/AIDS patients receiving high dose of the sulfonylurea co-trimoxazole for opportunistic infections. Whether co-trimoxazole at prophylactic dose would induce si...

    Bernold Kenteu, Jean Jacques N. Noubiap, Martine Claude Etoa, Marcel Azabji-Kenfack, Mesmin Dehayem and Eugene Sobngwi

    BMC Endocrine Disorders 2016 16:62

    Published on: 15 November 2016

  11. Research article

    The course of diabetes in children, adolescents and young adults: does the autoimmunity status matter?

    Initial classification of diabetes of young may require revision to improve diagnostic accuracy of different forms of diabetes.

    Rasa Verkauskiene, Evalda Danyte, Rimante Dobrovolskiene, Ingrida Stankute, Diana Simoniene, Dovile Razanskaite-Virbickiene, Audrone Seibokaite, Brone Urbonaite, Nijole Jurgeviciene, Astra Vitkauskiene, Valerie Schwitzgebel and Dalia Marciulionyte

    BMC Endocrine Disorders 2016 16:61

    Published on: 15 November 2016

  12. Research article

    Gastric bypass surgery reveals independency of obesity and diabetes melitus type 2

    Roux-en-Y gastric bypass surgery is widely applied to ameliorate morbid obesity, including diabetes in people with type 2 diabetes. The latter vanish a few days after surgery for many, but not in all patients ...

    Mogens Fenger, Dorte Lindqvist Hansen, Dorte Worm, Lisbeth Hvolris, Viggo B. Kristiansen, Elin Rebecka Carlsson and Sten Madsbad

    BMC Endocrine Disorders 2016 16:59

    Published on: 9 November 2016

  13. Research article

    The effect of lifestyle intervention in obesity on the soluble form of activated leukocyte cell adhesion molecule

    The aim of this study was to investigate the effect of a lifestyle intervention in obesity on the soluble form of the activated leukocyte cell adhesion molecule (sALCAM) and its association with metabolic para...

    Alba Sulaj, Johanna Zemva, Ulrike Zech, Annika Woehning, Maik Brune, Gottfried Rudofsky, Peter P. Nawroth, Thomas Fleming and Rüdiger von Bauer

    BMC Endocrine Disorders 2016 16:56

    Published on: 13 October 2016

  14. Research article

    Single-dose acarbose decreased glucose-dependent insulinotropic peptide and glucagon levels in Chinese patients with newly diagnosed type 2 diabetes mellitus after a mixed meal

    Acarbose slows down the intestinal absorption of carbohydrates, but its effects on the secretion of incretins are still poorly known. This study aimed to examine the effects of single-dose acarbose on the secr...

    Zhong Chen, Xiaoying Fu, Jian Kuang, Ju Chen, Hongmei Chen, Jianhao Pei and Huazhang Yang

    BMC Endocrine Disorders 2016 16:55

    Published on: 29 September 2016

  15. Research article

    Neonatal and obstetric outcomes in diet- and insulin-treated women with gestational diabetes mellitus: a retrospective study

    To evaluate the neonatal and obstetric outcomes of pregnancies complicated by gestational diabetes mellitus (GDM). Screening and treatment – diet-only versus additional insulin therapy – were based on the 2010...

    Sarah H. Koning, Klaas Hoogenberg, Kirsten A. Scheuneman, Mick G. Baas, Fleurisca J. Korteweg, Krystyna M. Sollie, Bertine J. Schering, Aren J. van Loon, Bruce H.R. Wolffenbuttel, Paul P. van den Berg and Helen L. Lutgers

    BMC Endocrine Disorders 2016 16:52

    Published on: 29 September 2016

  16. Research article

    Plantar pressures are higher in cases with diabetic foot ulcers compared to controls despite a longer stance phase duration

    Current international guidelines advocate achieving at least a 30 % reduction in maximum plantar pressure to reduce the risk of foot ulcers in people with diabetes. However, whether plantar pressures differ in...

    Malindu E. Fernando, Robert G. Crowther, Peter A. Lazzarini, Kunwarjit S. Sangla, Scott Wearing, Petra Buttner and Jonathan Golledge

    BMC Endocrine Disorders 2016 16:51

    Published on: 15 September 2016

  17. Research article

    Increased skin autofluorescence of children and adolescents with type 1 diabetes despite a well-controlled HbA1c: results from a cohort study

    Early identification of children and adolescents with type 1 diabetes at high risk for development of complications is important, as early intervention may prevent further deterioration. Here we investigate th...

    Josine C. van der Heyden, Erwin Birnie, Dick Mul, Sarah Bovenberg, Henk J. Veeze and Henk-Jan Aanstoot

    BMC Endocrine Disorders 2016 16:49

    Published on: 9 September 2016

  18. Research article

    Elevated circulating irisin is associated with lower risk of insulin resistance: association and path analyses of obese Chinese adults

    Evidence on the role of irisin in insulin resistance is limited and controversial, and pathways between them remain unknown. We aimed to examine the independent effects of circulating irisin and different adip...

    Xiulin Shi, Mingzhu Lin, Changqin Liu, Fangsen Xiao, Yongwen Liu, Peiying Huang, Xin Zeng, Bing Yan, Suhuan Liu, Xiaoying Li, Shuyu Yang, Xuejun Li and Zhibin Li

    BMC Endocrine Disorders 2016 16:44

    Published on: 29 July 2016

  19. Research article

    Development and validation of a Diabetes Risk Score for screening undiagnosed diabetes in Sri Lanka (SLDRISK)

    Screening for undiagnosed diabetes is not widely undertaken due to the high costs and invasiveness of blood sampling. Simple non-invasive tools to identify high risk individuals can facilitate screening. The m...

    P. Katulanda, N. R. Hill, I. Stratton, R. Sheriff, S. D. N. De Silva and D. R. Matthews

    BMC Endocrine Disorders 2016 16:42

    Published on: 25 July 2016

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